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DNA Repair Proteins: Components and Functions

Explore the key DNA repair proteins such as DDB1, RPA1, XPA, XPF, POLD, ERCC8, XAB2, GTF2H4 in the intricate process of maintaining genomic integrity. Learn about their roles, structures, and interactions.

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DNA Repair Proteins: Components and Functions

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  1. DDB1: damage-specific DNA binding protein 1, 127kDa, RPA1: replication protein A1, 70kDa, XPA: xeroderma pigmentosum, complementation group A, XPF: xeroderma pigmentosum, complementation group F, alias for ERCC4: excision repair cross-complementing rodent repair deficiency, complementation group 4, POLD: polymerase (DNA directed), delta 1, catalytic subunit 125kDa, ERCC8: excision repair cross-complementing rodent repair deficiency, complementation group 8, XAB2: XPA binding protein 2, TFIIH complex: Includes ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2), ERCC3 (excision repair cross-complementing rodent repair deficiency, complementation group 3), GTF2H4: general transcription factor IIH, polypeptide 4.

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