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An introduction to infectious diseases epidemiology Jon Otter, PhD FRCPath

An introduction to infectious diseases epidemiology Jon Otter, PhD FRCPath Imperial College London j.otter@imperial.ac.uk @ jonotter Blog: www.ReflectionsIPC.com Slides: www.jonotter.net.

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An introduction to infectious diseases epidemiology Jon Otter, PhD FRCPath

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  1. An introduction to infectious diseases epidemiology • Jon Otter, PhD FRCPath • Imperial College London • j.otter@imperial.ac.uk • @jonotter • Blog: www.ReflectionsIPC.com • Slides: www.jonotter.net

  2. Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi; the diseases can be spread, directly or indirectly, from one person to another (World Health Organisation)

  3. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  4. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  5. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  6. MRSA infection

  7. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  8. Clostridium difficileinfection

  9. Faecal microbiota transplant for recurrent CDI Patients with recurrent CDI randomised to FMT (n=16), vancomycin (n=12) or vancomycin + bowel lavage (n=13) van Noodet al. N Engl J Med 2013;368:407-415.

  10. Recurrent CDI is just the start… Xuet al. World J Gasteroenterol2015;21:102-111.

  11. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  12. CPE outbreak; total number of cases 8 cases first identified by clinical culture, 32 by screening culture; of these 32, 14 had a subsequent positive clinical culture Otter et al. Sci Rep 2017;7:12711.

  13. Cost of an outbreak - results Economic evaluation of a 40 case outbreak of CPE. Error bars represent range Otter et al. ClinMicrobiol Infect 2017;23:188-196.

  14. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  15. * HCAI = Healthcare-associated infection. ** ID = infectious diseases.

  16. Routes into infectious disease epidemiology

  17. Resources

  18. An introduction to infectious diseases epidemiology • Jon Otter, PhD FRCPath • Imperial College London • j.otter@imperial.ac.uk • @jonotter • Blog: www.ReflectionsIPC.com • Slides: www.jonotter.net

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