Food Security - Safety - Quality - Quantity More jobs and increased incomes National Level: sustainable economic and soc

1. Fundamental Objetives of Agribusiness in Brazil Food Security - Safety • - Quality • - Quantity More jobs and increased incomes National Level: sustainable economic and social development International Level: novel markets & frontiers of contribution to global sustainability

2. In 2004, Brazilian agribusiness accounted for: GDP EXPORTS 30.0% 40.4% JOBS 37.0% Sources: CEPEA-USP / CNA, MAPA e IPEA

3. Brazilian Agribusiness and GDP - 2004: Brazilian GDP (US$ 604.9 billion) Agribusiness’ GDP US$ 182 billion (30%) Non-Agribusiness’ GDP US$ 422.9 billion (70%) Sources: CEPEA-USP / CNA

4. Brazilian Exports (by value): Main Trading Partners(From December 2004 to November 2005) Source: MAPA

5. Ranking of Brazilian Production and Exports (2004) Sources: USDA, F. O. Licht

6. MINISTRY OF AGRICULTURE, LIVESTOCK & FOOD SUPPLYOrganization Chart

7. . Brazilian Agricultural Defense System Geographical Structure Headquarters State Agric. Authority Official Laboratory Harbor Airport Border Control

8. Agricultural Defense Activities Animal & Plant Health– oriented to production - emphasis on animal and plant health: Tools: GAP, plant and animal disease risk analysis, traceability & certification systems Quality & Safety – oriented to the consumer - emphasis on consumer health & satisfaction broader agricultural sustainability: Tools: GAP, GMP, SSOP, HACCP Inspections, zoonose controls, risk analysis, traceability & certification systems

9. Quality & Safety of Foods and Beverages - MAPA Program 0356 - • 14 Sub-programs, including animal- and plant-derived foods • Food quality and safety inspection (shared responsabilities with the Ministry of Health) • Enforcement of food quality and safety standards (shared responsabilities with the Ministry of Health) • Product certification and traceability • Analytical studies and surveillance • Inspector training • Technology transfer & processor training (EMBRAPA and partners) • May include support to research • Total budget ca. € 12 million (2005). A substantial increase expected for 2006.

10. Research & Development: EMBRAPA • The R&D arm of the Ministry of Agriculture, est. 1973 • 40 research units strategically located and product-oriented • 2168 researchers (1040 Ph.D., 1067 M.Sc.) • Multiple international partnerships • Present abroad since 1998 (initially financed by the World Bank): 2 international collaborative centers – LABEX: Beltsville, MD, USA Montpellier, France.

11. MAJOR LABEX COOPERATION AREAS

12. EMBRAPA Labex: An Inovative Concept • COOPERATION AREAS • Precision Agriculture • Integrated Animal Health Control • Integrated Plant Health Control • Soil & Water Resources Management • Global Climate Changes • Biotechnology & Intellectual Property • Advanced Molecular Biology Tools • Novel Uses for Agricultural Products • Modeling • Nanotechnology • Genetic Resources • FOOD SAFETY

13. Scope – potential pathogens in meat, pork and dairy products Partners – Embrapa Dairy Cattle, Food Technology, Tropical Agroindustry, Goats, Swine & Poultry research centers. Universities. LABEX-USA Food Safety Reseach Network ERRC, Wyndmoor, PA

14. University of Wisconsin-MadisonFood Research Institute Fate of E. coli O157: H7 in Home-Made Dried Beef Faith, LeCountour, Bonnet, Cacioglu, Luchansky Int. J. of Food Microbiology, 1998

15. Rutgers, The State University of New Jersey, USA L. monocytogenes: Bonnet & Montville, Lett. Appl. Microbiol, 2005

16. ATR L. Monocytogenes: Food Antimicrobial Resistance Bonnet & Montville, Lett. Appl. Microbiol, 2005

17. Increased ATP in ATR+ Cells Bonnet & Montville, Appl. Environ. Microbiol., 2005 (accepted)

18. Conclusion from Mechanistic Studies ATR-induction Lactic acid enters cells Decreases PMF Protects cells to nisin Downregulates & other PMF-driven FoF1 ATPase antimicrobials Spares vital ATP

19. Enterobacter sakazakii in powdered infant formulae Bacterial stress issues (response to dehydration, sugar accumulation) High morbidity Largely disseminated 11 strains studied in 16 commercial products USDA-ERRCPredictive Microbiology:Modeling microbial development in foods for risk assessment

20. USDA Pathogen Modeling Program PMP • Developed by the Center for Microbial Modeling and Informatics (CEMMI), led by Dr. Mark Tamplin, at the Eastern Regional Research Center (ERRC), Wyndmoor, PA.The program is free for public use (www.arserrc.gov) • The PMP uses published models to generate predictions of microbial (L. monocytogenes, S. aureus, C. perfringens, E. coli 0157: H7 etc) development in several relevant food systems • Once the food system is chosen, input variables include time, initial microbial load, temperature, Aw, NaCl concentration. The output, immediately generated, will give the predicted microbial populations (and the confidence intervals) reached for the specified conditions • We translated the PMP to Portuguese, making it widely available for brazilian food processors – availability 2006 • Brazil plans on contributing with the PMP by conducting research with food systems of national and multi-national interest. This will add new modelsto further widen the PMP scope

21. Strategic Network of Agricultural Risk Analysis- REARA - • Microbial food safety (S. aureus, Salmonella spp., L. monocytogenes, E. sakazakii). Development of risk analysis for specific pathogens and development of predictive models for specific pathogens in relevant food systems (contribution to the PMP) • Chemical food safety (aflatoxins, other mycotoxins and pesticide residues). Development of toxin production models and risk analysis for pesticide residues • Real-time CCP (HACCP) monitoring • Consumer Interface

22. Research Projects • Development of Sampling Plans for Aflatoxin Control in Brazil Nuts – MAPA and Embrapa. Approved by FINEP – €300.000 – initial results to be presented in 2006 to CODEX ALIMENTARIUS. 2 years • Development of an Integrated Program for Aflatoxin Control in Brazil Nuts – MAPA, Embrapa and EU partners – producer training, production logistics, mathematical modeling of aflatoxin production – 2 years. Coordination: Catherine BRABET, INRA. Submitted • Chemical Profiles of Brazilian Spirits – Cachaca – MAPA and University of Sao Paulo-Sao Carlos – Prospective full financing by MAPA of €90.000 • Risk Assessment of Pesticide Residue Levels in Selected Fruits and Vegetables – MAPA, Universities and official laboratories. Forthcoming in 2006, to be conducted in conjunction with the Ministry of Health surveillaces performed at retail level

23. ACKNOWLEDGEMENTS • Dr. Hartmut Waldner – German Federal Office for Food Safety • Other SAFEFOODERA and EU colleagues • Lithuanian authorities • Dr. Mark Tamplin, CEMMI-ERRC-USDA • Dr. John Luchansky, MFS-ERRC-USDA • Dr. John Cherry, ERRC-USDA • Colleagues and students at CEMMI-ERRC-USDA

24. ACKNOWLEDGEMENTS (MAPA) • Dr. Gabriel Maciel, Secretary of Agricultural Defense • Dr. Alvaro Silva, Director, Plant Programs • Fabio Fernandes, B.Sc. • Drs. Odilson, A. Pontes (SRI), P. Arraes (LABEX) • My team

25. We look forward to expanding our food quality and safety programs toward the unique opportunity made possible by SAFEFOODERA. Thank you!

26. Contact InformationDr Marcelo BonnetDirector, Plant Products Inspection DepartmentSecretatiat of Agricultural DefenseMinistry of Agriculture, Livestock & Food SupplyEsplanada dos Ministerios, Anexo A, sala 337BBrasilia DF 70000 BrazilTel +55 61 3218 2323Tel + 55 61 3322 3742mbonnet@agricultura.gov.brfernandes@agricultura.gov.brmbonnet2002@yahoo.com