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Classic Lattice Degeneration. Perivascular Lattice. Photocoagulation spots in moderate pattern. Cryotherapy. Vitreous Anomoly. Attached with Silicone Oil. Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey.
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Stickler GB, Hughes W, Houchin P. Clinical features of hereditary progressive arthro-ophthalmopathy (Sticklersyndrome): a survey. Genet Med. 2001 May-Jun;3(3):192-6. Early diagnosis and intervention for retinal detachments can preserve vision.
Retinal Detachment and Prophylaxis in Type 1 Stickler Syndrome Ang A, Poulson AV, Goodburn SF, Richards AJ, Scott JD, Snead MP.Ophthalmology. 2008 Jan;115(1):164-8.
Shapiro Recommendation Monitor Q 3 months to catch RD early EUAs as needed to get view of periphery Test each eye regularly Educate for Signs of breaks and RDs Educate of continued high risk (5-10%) Treat with laser from ora to anterior equator or most posterior pathology. Consider randomizing to cryotherapy
Choice of Intervention • Peripheral Cryotherapy • Peripheral Laser Photocoagulation • Encircling Scleral Buckle • Treatment of Pathologic • PVD • Monitoring
Questions for Physician Education • Why is detection and counseling important ? • What are the triggers for suspicion? • What diagnostic complexity is posed by COL2A1:Exon2 disease: ocular predominant • When and How is Stickler outcome improved ? • What are diagnostic pearls ?