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INTRODUCTION. DEFINITIONEPIDEMIOLOGYAETIOLOGYPATHOGENESISCLINICAL FEATURESMANAGEMENTCOMPLICATIONSPROGNOSIS. DEFINITION . DEFINE JAUNDICETYPES OF JAUNDICE- CLASSIFYWITH RESPECT TO THE PATHOGENESIS- THE LIVER IS CENTRALPRE-HEPATIC, HEPATIC, POST-HEPATICOBSTRUCTIVE JAUNDICEAMENABLE/TREATABL
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1. SURGICAL JAUNDICE Dr. ADEFEMI O. AFOLABI
HEPATOBILIARY & ENDOCRINE DIVISION
DEPARTMENT OF SURGERY
COLLEGE OF MEDICINE
UNIVERSITY OF IBADAN,
&
UNVERSITY COLLEGE HOSPITAL, IBADAN, NIGERIA.
2. INTRODUCTION DEFINITION
EPIDEMIOLOGY
AETIOLOGY
PATHOGENESIS
CLINICAL FEATURES
MANAGEMENT
COMPLICATIONS
PROGNOSIS
3. DEFINITION DEFINE JAUNDICE
TYPES OF JAUNDICE- CLASSIFY
WITH RESPECT TO THE PATHOGENESIS- THE LIVER IS CENTRAL
PRE-HEPATIC, HEPATIC, POST-HEPATIC
OBSTRUCTIVE JAUNDICE
AMENABLE/TREATABLE BY SURGERY
4. EPIDEMIOLOGY DISTRIBUTION
GEOGRAPHICAL
AGE
GENDER
5. AETIOLOGY AGE
GENDER
GEOGRAPHICAL
LUMEN- INTRA-, MURAL, EXTRA-
PNEMONIC- TINCABED
6. AETIOLOGY CHOLEDOCHOLITHIASIS
CHOLEDOCHAL CYST
BILIARY ATRESIA & OTHER BILIARY ANATOMICAL VARIATIONS
7. AETIOLOGY NEOPLASMS- CARCINOMA, HEAD OF PANCREAS, CHOLANGIOCARCINOMA,
PERIAMPULLARY CARCINOMA, CARCINOMA OF THE DUODENUM
LYMPHADENOPATHY-PORTA HEPATIS
TRAUMATIC- POST CHOLECYSECTOMY
8. PATHOGENESIS AETIOLOGICAL FACTORS-CALCULOUS, NEOPLASTIC
BILIARY TREE OBSTRUCTION
STASIS
HEPATOCELLULAR DYSFUNCTION
CHOLANGITIS
MALABSORPTION
9. CLINICAL FEATURES WITH RESPECT TO AETIOLOGY &
THE EFFECTS OF OBSTRUCTION
JAUNDICE, PRURITUS, DARK URINE, PALE STOOLS, PAIN/COLIC, WEIGHT LOSS, VOMITING, ANOREXIA, ANAEMIA, ABDOMINAL MASS, HEPATOMEGALY, GALL BLADDER DISTENSION, ASCITES
10. MANAGEMENT CONFIRM CLINICAL DIAGNOSIS
ASSESS PHYSIOLOGICAL STATUS
INVESTIGATE FOR SURGERY
11. INVESTIGATIONS ABDOMINAL ULTRASOUND
ABDOMINAL CT SCAN
ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATO-
-GRAPHY
12. INVESTIGATIONS SERUM BILIRUBIN, ALKALINE PHOSPHATASE, AST, ALT, ALBUMIN, GLOBULIN, CHOLESTEROL
PROTHOMBIN TIME (INR), PTTK
URINALYSIS, SERUM E/U& Cr.,
13. CT ABDOMEN
14. CT ABDOMEN
15. DISTENDED GALL BLADDER
16. BILIARY BYPASS
17. CT ABDOMEN(DA)
18. LUNG METASTASES OF GALL BLADDER CANCER
19. INVESTIGATIONS FULL BLOOD COUNT, GROUP & CROSS MATCH BLOOD
HAEMOGLOBIN ELECTROPHORESIS
BLOOD CULTURE
CHEST X-RAY, ABDOMINAL X-RAY
TRANSHEPATIC CHOLANGIOGRAPHY
20. TREATMENT OPTIMISE THE PATIENT-CORRECT ANAEMIA, ELECTROLYTE ABNORMALITIES, REHYDRATE, BLEEDING DISORDER(VITAMIN K), NUTRITION-CHO, PROTEIN,
BOWEL PREPARATION, PERIOPERATIVE ANTIBIOTICS
21. TREATMENT CHOLEDOCHOLITHIASIS-
INTRAOPERATIVE CHOLANGIGRAPHY
CHOLECYSTECTOMY-
OPEN/LAPAROSCOPIC,
EXPLORATION OF COMMON BILE DUCT, INSERTION OF T-TUBE-MANAGEMENT OF TUBE,
ENDOSCOPIC SPHINCTEROTOMY
CARCINOMA- WHIPPLE’S PROCEDURE,
22. T-TUBE CHOLANGIOGRAM
23. PALLIATIVE TREATMENT ENDOSCOPIC INSERTION OF BILIARY STENT
BYPASS SURGERY
CHOLECYSTOJEJUNOSTOMY OR CHOLEDOCHOJEJUNOSTOMY,GASTROJEJUNOSTOMY, & JEJUNOJEJUNOSTOMY-SIDE TO SIDE OR ROUX-EN-Y
24. COMPLICATIONS OF TREATMENT BLEEDING
SEPTICAEMIA
RENAL FAILURE
ANASTOMOTIC DEHISCENCE
OTHERS
25. PROGNOSIS DEPENDS ON THE AETIOLOGY AND THE STAGE OF PRESENTATION
26. CONCLUSIONS
DO IT RIGHT THE FIRST TIME, BECAUSE LIFE IS NOT A DRESS REHEARSAL
BOB GASS