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Anti-inflammatory Meds. Megan Rohm, BSN, RN. Inflammatory Response. Protects the body from injury and pathogens Uses chemical mediators to produce the reaction that helps destroy pathogens and promote healing. Anti-inflammatory Agents.
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Anti-inflammatory Meds Megan Rohm, BSN, RN
Inflammatory Response • Protects the body from injury and pathogens • Uses chemical mediators to produce the reaction that helps destroy pathogens and promote healing
Anti-inflammatory Agents • Block or alter the chemical reactions associated with the inflammatory response
Types of Anti-inflammatory Agents • Corticosteroids: used systemically to block the inflammatory and immune systems • Antihistamines: block the release of histamine in the initiation of the inflammatory response • NSAIDS
Salicylates- NSAID • Can block the inflammatory response • Have antipyretic (fever-blocking) properties • Have analgesic (pain-blocking) properties
NSAIDs • Provide strong anti-inflammatory and analgesic effects • Sold over the counter, which may lead to abuse
Common Salicylates • Aspirin (Bayer,etc.): treats inflammatory conditions • Balsalazide (Colazal): new drug that treats ulcerative colitis • Choline magnesium trisalicylate (Trilisate): treats mild pain and fevers as well as arthritis • Cholinesalicylate (Arthropan): treats mild pain and fevers as well as arthritis • Mesalamine (Pentasa, etc.): treats inflammation of the large intestine • Olsalazine (Dipentum): converted to mesalamine in the colon; has the same direct anti-inflammatory effects • Salsalate (Argesic, etc.): treats pain, fever, and inflammation • Sodium thiosalicylate (Rexolate): treats episodes of acute gout and muscular pain as well as rheumatic fever
NSAIDs Indications • Relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis • Relief of mild to moderate pain • Treatment of primary dysmenorrhea • Fever reduction
Contraindications to NSAIDs • Presence of allergy to any NSAID or salicylate • Cardiovascular dysfunction or hypertension • Peptic ulcer or known GI bleeding • Pregnancy and lactation • Caution with renal or hepatic dysfunction
Mnemonics • NSAIDSNo alcoholSide effects (teach them to report any dark tarry stools, coffee-ground or bloody emesis, GI distress, tinnitus) ASA sensitivity - do not giveIbuprofen, indocin are a few examplesDo take with foodStop 5-7 days before surgery
Mnemonics • Empty stomach Penicillin Sulfa drugs Tetracycline
Mnemonics • Antacids- FaCT Fluoroquinolone a CephalosporinsTetracyclines
Mnemonics- photosensitivity • Terrible Fucking Sunburn • Tetracycline Fluroquinolines Sulfonamides
Mnemonics- ototoxicity /peak and trough • AudioVisual m a I n n c o o g m l y y c c i o n s I d e
Mnemonics and study aids • http://www.studystack.com/gsearch.jsp?cx=partner-pub-4909676113151654%3Ayhlp7k-59l2&cof=FORID%3A9&ie=UTF-8&q=nursing+anti+biotic&sa=Search&siteurl=www.studystack.com%2FNursing#987 • http://www.scribd.com/doc/22593365/Nursing-Mnemonics-09 • http://jeopardylabs.com/play/anti-infectives