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Gaucher Disease: Bone Imaging

Gaucher Disease: Bone Imaging. DXA (Dual-Energy X-ray Absorptiometry). DXA Spine Image and Test Results. DXA Hip Image and Test Results. Absorptiometry. DXA: Trabecular Bone Change. BMD ↓. BMD ↓. BMD ↓. DXA: Cortical Bone Change. BMD ↓. BMD ↓. BMD ↓. Computed Tomography.

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Gaucher Disease: Bone Imaging

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  1. Gaucher Disease: Bone Imaging

  2. DXA (Dual-Energy X-ray Absorptiometry)

  3. DXA Spine Image and Test Results

  4. DXA Hip Image and Test Results

  5. Absorptiometry

  6. DXA: Trabecular Bone Change BMD ↓ BMD ↓ BMD ↓

  7. DXA: Cortical Bone Change BMD ↓ BMD ↓ BMD ↓

  8. Computed Tomography

  9. Whole-body CT Scan With Vertebra

  10. Close-up of Vertebra

  11. Forearm CT Scan

  12. Image of Radius and Ulna

  13. Quantitative Computed Tomography (QCT): Trabecular Bone Change TBD ↔ TBD ↓ TBD ↓

  14. QCT: Cortical Bone Change CBD ↔ CBD ↔ CBD ↓

  15. Possible Conditions for Bone Loss Resorption ↑ Formation ↔ Resorption ↔ Formation ↓ Negative Balance Resorption ↑ Formation ↓

  16. 0.8 0.7 BMD [g/cm2] 0.6 0.5 1 2 3 Measurement Follow-up Measurements

  17. 0.85 sd 0.80 D ³ 2.8 sd (p>95%) D 0.75 BMD [g/cm2] 0.70 0.65 0.60 1 2 Measurement Point Significant Differences

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