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CASE 2. 49 yo man HIV+ since 1993 CD4 Nadir 120/7% Smoker of 45 pack years. CASE 2. Antiviral History. CASE 2. 2012 Depression x yrs Fatigue x yrs Arthralgia/Bone pain. CASE 2. CASE 2. No family history of endocrine abnormalities No obvious cancer
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CASE 2 • 49 yo man • HIV+ since 1993 • CD4 Nadir 120/7% • Smoker of 45 pack years
CASE 2 Antiviral History
CASE 2 2012 • Depression x yrs • Fatigue x yrs • Arthralgia/Bone pain
CASE 2 • No family history of endocrine abnormalities • No obvious cancer • No ingestion of meds known to cause high calcium • No calcium supplements, vitamins, herbal remedies, OTC’s or calcium carbonate containing products
CASE 2 June 2012 • Of note, drinks 4L of milk daily!!!! • On Ranitidine for GERD • TOLD TO STOP MILK
CASE 2 • Felt much less tired with decreased arthralgia/bone pain when milk consumption eliminated
CASE 2 Further Workup • Serum/urine immunelectrophoresis • normal • CT Chest/Abdo • Normal
CASE 2 Further Workup • U/S Thyroid • Small nodule • No change in size with 3mos f/u • 24 hr urine for calcium • Elevated urinary calcium 8.6 mmole/l (1.2-6.2)
CASE 2 Diagnosis • ?mild primary hyperparathyroidism exacerbated by excessive milk consumption