POST-GRADUATE DIPLOMA IN

1. POST-GRADUATE DIPLOMA IN “CLINICAL EMBRYOLOGY AND ASSISTED REPRODUCTIVE TECHNOLOGY” OFFERED BY: DIVISION OF BIOLOGICAL SCIENCES School of Natural Science Bangalore University Bangalore, Karnataka India

2. Overview of the Presentation • Course Offered By • Title of the Course • Highlights of the course • Duration of the course & Eligibility • Course Matrix, FEE, Intake and Scheme of Examination • Expertise available for the course • Infrastructure available for the course • requirements of the course • Budgetary INSIGHTS of the course • Regulatory Approvals and Mou’s • Response and Possible outcomes

3. Course Offered By DIVISION OF BIOLOGICAL SCIENCES MOMSOON FERTILITY & IVF CENTER Pvt. Ltd. School of Natural Science, Bangalore University, Bangalore - 560 056 (A unit of RR Medicare Services), 9th Main Jayanagar 4th Block, Bangalore - 560 011 In collaboration with Title of the Course ONE YEAR POST-GRADUATE DIPLOMA IN “CLINICAL EMBRYOLOGY AND ASSISTED REPRODUCTIVE TECHNOLOGY”

4. Highlights of the course • What is new about this Course ? It is an unique and innovative course blending Applied Biology and Clinical Medicine • The Uniqueness • Reproductive Medicine involving Oogenesis, Spermatogenesis, Endocrinology, Ovarian Stimulation with exogenous Hormones – • Andrology, Oocyte & Sperm Fertilization in Vitro, Embryo Culture, Embryo Grading & Transfer – • This unique blend of both the above chapters is essential for ‘THE CLINICAL CHAPTERS’. ‘THE LABORATORY • CHAPTERS’. Clinical Embryology & Assisted Reproductive Techniques

5. Highlights of the course Contd.…. A Collaborative Curriculum • Laboratory role is an important integral part of the treatment protocols in this technology • Non compliance of Laboratory role shall be a handicap to the clinician • Laboratory People are handicapped unless they are taught important clinical parameters • Unless personnel is equipped with both Laboratory and Clinical knowledge implementation of protocols shall be incomplete • Comprehensive Theory & Practical’s can make Clinicians/ Biologists more proficient in managing the problem

6. Highlights of the course Contd.…. Current Statistical Scenario • It is estimated that around 18 – 20 % of any population is infertile/ Sub fertile throughout the World. • Male Infertility is on the rise over the past 5 decades, with a gradual decline in the Sperm Count. • 40% of the infertility problems are male oriented and the remaining 60% accounts to female partner and several other disorders. • More than 4 million babies are born globally through Assisted Reproductive Technology (ART) • The success rate of ART is around 30 - 35% globally. However, comparatively it is quite low in India because of untrained/ unqualified personnel involved in ART.

7. Highlights of the course Contd.…. Current Statistical Scenario • According to National data of Assisted Reproduction in India (NARI), 2001-2005, published by ISAR (The Indian Society of Assisted Reproduction), a large number of IVF pregnancies (more than 40%) end up in miscarriages as compared to 5% in Western countries. • At present, more than 500 IVF Centres (most of them private except AIIMS) are functioning in India and there are only around 100 qualified and well experienced Embryologists in our Country. • To bridge the gap it is very much essential to provide the country a trained human resource through this innovative course

8. Duration of the course And Eligibility • One Year PG Diploma Course • Candidates who have completed MBBS, BVSC, M.Sc. (Zoology, Biotechnology, Life sciences, Biological Sciences, Molecular biology, Applied genetics) are eligible • Eligibility Criteria – Minimum 50% in Aggregate the qualifying exam Course Matrix, FEE, Intake & Scheme of Examination • The course consists of two theory papers, two practical's and Case study/ Hands-on Training. • Course Fee as per University guidelines • Intake will be limited to 20 + sponsored candidates

9. Course Structure Paper – 1 : BASIC EMBRYOLOGY & ANDROLOGY • Infertility and sub fertility • The Genesis of two sexes • Testicular Function • Ovarian function • Reproductive Messengers • The Regulation of Gonadal function Paper – 2 : Practical's related to above topics Paper – 3 : ASSISTED REPRODUCTIVE TECHNIQUES • Fertilization and Implantation • Assisted Reproduction and In-vitro Fertilization • Stimulation Protocols Paper – 4 : Practical's related to above topics Paper – 5 : CASE STUDY AND HANDS-ON TRAINING

10. Expertise available for the course Dr. H.P. PUTTARAJU - Course Coordinator Professor, Division of Biological Sciences, School of Natural Science, Bangalore University • Specialization-Genetics • More than 30 years of Research and PG teaching experience. • Published more than 80 research papers in reputed journals, 3 books. • Guided successfully 14 Ph.D.’s and 7 M.Phil research degrees. • Received grants over 50 Lakhs for research projects from various funding agencies viz., DST, DBT, UGC, BRNS, ICMR and Bangalore University. • Recipient of several awards and fellowships/ recognitions for his research contributions (Sir C.V. Raman Young Scientist – 2004; Commonwealth Fellowship – 1997) • Visiting scientist, University of Bremen, Germany under DFG-INSA bilateral exchange programme 2010, • Member of NAAC Peer Review Committee; Evaluation Award Committee- VGST, Govt. of Karnataka, • Reviewer of research articles for several reputed journals • And so on…….

11. Expertise available for the course Dr. Y. RAVINDRANATH Senior Embryologist and Scientific Director, Momsoon Fertility & IVF Centre, Bangalore • Ph.D. in Human Genetics • More than 18 years of IVF/ ICSI experience in India and abroad • Extensive training in well reputed Institutions of the world, like the Bourn Hall Clinic, Cambridge, U.K, which produced the World’s first IVF Baby, Jones Institute of Reproductive Medicine, Norfolk, Virginia, USA, University College of London and Hammersmiths Hospital, London, U.K, • Got trained in ICSI-Intracytoplasmic Sperm Injection, in Belgium under Carl Spiessens of Catholic University Hospital, Leuven and under Prof. Brian Dale, InstitutZoologica, University of Naples, Italy. • He is a member of ALPHA - Scientists in Reproductive Medicine, a World Body based in U.K. and ESHRE – European Society of Human Reproduction and Embryology, a World Body based in Belgium, E.U. • Instrumental in starting first IVF Centres in Hyderabad, Mangalore, Mysore , Shimoga, Kurnool in India and the first IVF Centres in Riyadh, Kingdom of Saudi Arabia and in Kuwait.

12. Expertise available for the course Dr. Vijaykumar, MD • Highly qualified and experienced IVF Specialist. • Worked for 5 years in a very reputed IVF Centre in Bangalore • Visiting IVF Specialist in many Centres in Karnataka and Andhra Pradesh. • Has many IVF babies to his credit. • Instrumental in organizing few Hands on Workshops in Reproductive Medicine for Clinicians from South India. Dr. SantoshGuptha, MD;Fellow in Reproductive Medicine Dr. SabithaGirish, MD • Consultant Gynaecologist and Specialist in IVF and Infertility, Momsoon Fertilty & IVF Center • Trained in IVF and Reproductive Medicine in a very reputed IVF Centre of Bangalore. • Made a reputation with her skills and management in Fertility procedures. • Specialized in Donor Oocyteprogrammes and Surrogacy.

13. Infrastructure Available of the course • Spacious well equipped building with state of the art laboratories • Well equipped class rooms with interactive display units (Projectors) • Trinocular microscopes with optical imaging system for image displaying during lectures for better understanding and interactive learning • Good Laboratory Practices with high sterile and hygienic conditions. • Essential basic instruments such as CO2 Incubator, Micromanipulator, Microscopes, Micropipettes, Hot plate, Centrifuge, Water Bath, Dry Bath, Mixer or Shaker, Adjustable Volume Pipettes, Cryogenic Equipment, Micro needle puller, Anti-vibration Platform and Table, Ice flakers

14. REQUIREMENTS of the course FACULTY – (2) (on actual basis) Two dedicated and full time faculties to train the students on basic and applied aspects of In Vitro Fertilization and Assisted Reproductive Technology Infrastructure – (For Laboratory Set up) Partitioning of Retrieval room, Embryology laboratory, Cryopreservation room. Major Equipments - (2) Laser System for Assisted Hatching & Embryo Biopsy (~ 14 lakhs) Real Time – PCR (~ 18 lakhs) Justification for Equipments : The above mentioned equipments are very essential for Pre-implantation Genetic Diagnosis for Chromosomal anomalies and Single gene disorders

15. Regulatory Approvals and Mou’s MoU b/w Biological Sciences, & Momsoon Fertility Center Certification by BBMP Health Dept., Govt. of Karnataka Faculty of Science Approval, Bangalore University Certification by Karnataka State Pollution Control Board Proceedings of BOS – Biological Sciences, Bangalore University

16. Initial Response and Possible outcomes • Response to this course has been encouraging with the University/ Academic bodies, IVF centers/ Gynecologists‘ all welcoming the idea to initiate such an innovative course in Traditional Universities which addresses Global and National priorities. • The proposed course bridges the crucial gap between Clinicians and Biologists and will be instrumental in providing the trained manpower to combat the raising infertility problem in India. • The most encouraging gesture has been from UGC and we are grateful for inviting us to give a brief presentation about our Course in the interface meeting with the Expert Committee.

17. THANK YOU