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Learn about cell division and the crucial phases of mitosis in Chapter 8. Explore the differences between chromosomes and chromatin in a simple analogy.
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Cell Reproduction Chapter 8
Chromosomes Vs. Chromatin
Think of it like Cookies!
Chromatin MAKES Chromosomes
Our cells are constantly needing to replace themselves. For example, when we get a paper cut or any kind of cut, those cells need to be replaced. Also, cells in your stomach lining constantly need to be replaced, and even bone marrow cells.
Cell Division: What is it?
The Cell Cycle is a sequence of separate periods of __________ & __________ The period where the cell grows in size, metabolizes, and spends a majority of its life is _______________ Also, during this period, the chromosomes are ___________ to prepare for cell division. Division Growth INTERPHASE duplicated
The period where the cell undergoesnuclear division and creates 2 daughter cells is called ____________ Each daughter cell contains a ____________ set of the parent cell’s chromosomes. MITOSIS Complete
Cell Cycle 75% of a cell’s life is spent in Interphase Which phase of the cell cycle takes the longest? Copies its chromosomes
G1 S G2 Cell Cycle
“Checkpoints” = stop & go-ahead signals to regulate the cycle • Regulatory molecules, usually enzymes (protein kinases) • To become active kinases need a cyclin to trigger them • Often called “Cdks” (cyclin-dependent kinases)
PROPHASE • The first phase = ____________ • This is the ________ phase (OF MITOSIS) • During this phase, chromatin coils to form visible _____________ • Each chromosome is made up of ___ sister chromatids and are held together by a __________ • *Remember: The chromosomes are duplicated in ____________ to prepare for cell division longest chromosomes 2 centromere Interphase
Chromosome The TWO together are One Chromatid Duplicated Chromatid sister chromatids
nuclear • In addition, the ________ envelope starts to disappear and the __________ disintegrates. • In animal cells, ___________ migrate to opposite ends of the cell and ________ ________ begin to form. • In plant cells _______ _______ form without centrioles. nucleolus centrioles spindle fibers Spindle fibers
METAPHASE • The Second Phase = _____________ • The chromosomes begin to line up along the _________ of the cell • The spindle fibers _______ to the centromeres. • Each chromatid has its own spindle fiber attached Equator attach
ANAPHASE • The Third Phase = ____________ • This marks the ___________ of sister chromatids. • The centromeres ______ and the ______ ___________ are pulled apart to opposite poles of the cell by shortening spindle fibers separation split sister chromatids
TELOPHASE The Fourth Phase = ______________ Here two distinct _________ cells start to form. In addition, the _____________ unwind, the spinder fibers ______ down, the _________ reappears, a new nuclear __________ forms, and a new double __________ begins to form between the two nuclei. daughter chromosomes break nucleolus envelope membrane
Cytokinesis • the division of ____________ • Toward the end of telophase in animal cells, the plasma membrane _______ in along the equator • In plant cells, a ____ _________ forms around each cell and new cell ______ form on each side of the cell plate until separation is complete. cytoplasm pinches cell membrane wall
Now the cells are separated, they will continue in the cell cycle and enter __________ interphase