'1mg kg' presentation slideshows

Pediatric Altered Level of Consciousness

Pediatric Altered Level of Consciousness. Terms. Resus Cocktail. Basics A B C IV, O2, Monitor FS EKG CXR Blood Gas +/- US. Resus Cocktail. Basics A B C IV, O2, Monitor FS EKG CXR Blood Gas +/- US. Quiz. Pediatric Resuscitative Drugs. Cardiac Resuscitative (PALS) Drugs.

1.73k views • 47 slides

Rapid Sequence Intubation

1.12k views • 45 slides

Sedation and Analgesia for ED101

Sedation and Analgesia for ED101. Kalpesh N. Patel, MD Dept. of Pediatric Emergency Medicine August 1, 2007. Objectives. To review sedation/analgesia drugs, doses, and nursing pain protocols To review pre-sedation workup and checklist

718 views • 39 slides

Developmental Pharmacokinetics of Diclofenac for Acute Pain

Developmental Pharmacokinetics of Diclofenac for Acute Pain. Standing JF , Howard RF, Johnston A, Savage I, Wong ICK. Diclofenac. NSAID pKa ~ 4 Oral F (unchanged) = 60% Protein binding > 99.7% (Davies 1997) Linear PK between 50 and 150mg (Lau 1989)

458 views • 38 slides

Anesthesia For Adeno -tonsillectomy

Anesthesia For Adeno -tonsillectomy. Presented by Ravie Abdelwahab. Reviewed by Dr. Amir Salah M.D. Historical Review. Tonsillectomy is one of the oldest surgical procedures known to man.

678 views • 27 slides

Sedation, Analgesia and Paralytics in the ICU

Sedation, Analgesia and Paralytics in the ICU. What is used for what?. Analgesic Pain control Always should be first before sedation Sedative Achieve sedation, anxiolysis , amnesia, altered consciousness Paralytic Prevents movement Never should be used without analgesia and sedation.

277 views • 21 slides

Pathophysiology and Management of Hypercyanotic or TET spells

Pathophysiology and Management of Hypercyanotic or TET spells. Leanne Meakins RN, MN, NP Congenital Cardiac Symposium 25 October 2013. Objectives. Review underlying anatomy Initial treatments Specific treatments and nursing considerations. Anatomy. Hypercyanotic Spells.

1.47k views • 16 slides

EQUINE CRYPTORCHIDECTOMY

EQUINE CRYPTORCHIDECTOMY. Pre-operation Implications. What is Cryptorchidism?. Cryptorchidism is the failure of one or both testes to descend into the scrotum and is the most common non-lethal developmental defect of equids.

971 views • 15 slides

Case Evaluation

Case Evaluation. How do you think you did? What do you think you did well? What would you have done differently? How do you think your colleagues did?. Diagnosis?. Intractable Headache Intracranial hemorrhage Hypercoagulable state. General Assessment of the Headache Patient.

186 views • 10 slides

Study on the anticonvulsant activity of Pentazocine in albino rats

Pentazocine, which is known to act as an agonist at kappa opioid receptors and a weak antagonist or a partial agonist at mu receptors has shown significant anticonvulsant activity in MES test and abolition of this anticonvulsant activity by high dose but not by low dose of Naloxone. The present study was designed to compare the anticonvulsant effect of Pentazocine with standard Sodium Valproate in albino rats. An attempt was also made to determine the possible opioid receptor mechanism involved. 30 albino rats of either sex weighing 150-200 gms were selected and randomly divided into 5 equal groups. Maximal Electroshock (MES) seizures were induced in albino rats via trans auricular electrodes (120mA, 0.2 seconds). Each rat was pretreated at 30 minute before MES test with the drugs intraperitoneally. The different groups were group 1 receiving Propylene glycol (0.5ml/kg), Group 2 receiving Sodium Valproate (300mg/kg), group 3 receiving Pentazocine (30mg/kg), group 4 receiving Pentazocine (30mg/kg) and Naloxone (0.1mg/kg), group 5 receiving Pentazocine (30mg/kg) and Naloxone (1mg/kg). Data was statistically analysed by Mann Whitney test and ANOVA. Intraperitoneal administration of Pentazocine resulted in reduction of different phases of convulsions during the MES method. The anticonvulsant effect of Pentazocine was antagonized by the high dose Naloxone (1mg/kg) but not by low dose (0.1mg/kg) of intraperitoneal Naloxone. The results suggest that Pentazocine has anticonvulsant activity which is mediated by kappa receptors. Naloxone in high dose is known to block kappa receptors, thereby blocking the anticonvulsant effect of pentazocine.

105 views • 5 slides

VC (100 m L, SC, 2 times a week)

Supplemental Fig. 1. 0. 3. 7 (weeks). VC (100 m L, SC, 2 times a week). ZA (0.1mg/kg/w, SC). MEL (7mg/kg/w, IP). ZA/MEL (ZA: 0.1mg/kg/w; MEL: 7mg/kg/w). ZA/DEX (ZA: 0.1mg/kg/w; DEX: 5mg/kg/w SC). 9-week-old mice. Tooth extractions of the Maxillary 1st molars. euthanasia.

89 views • 1 slides