'Beta lactamases' presentation slideshows

MECHANISMS OF ACTION OF ANTIBIOTICS

MECHANISMS OF ACTION OF ANTIBIOTICS. BACTERIOSTATIC AGENTS. Sulfonamides Drugs inhibiting protein synthesis except aminoglycosides (macrolides, chloramphenicol, tetracyclines etc). BACTERICIDAL AGENTS. Beta lactams (penicillins, cephalosporins, imipenem) Trimethoprim/sulfamethoxazole

3.24k views • 72 slides

Antibiotics

Antibiotics. ???? ???? ?????. ?????? ???? ?????. Resistance mechanism. Beta-lactamases (eg. ESBLs, Carbapenemase) Target modifying enzymes (PBP) Drug modifying enzymes Porin loss Efflux pump VISA/VRSA VANs. Resistance mechanism Penicillin Binding Protein (PBP).

1.1k views • 71 slides

Antibiotics

Antibiotics. ???? ???? ?????. ?????? ???? ?????. Resistance mechanism. Beta-lactamases (eg. ESBLs, Carbapenemase) Target modifying enzymes (PBP) Drug modifying enzymes Porin loss Efflux pump VISA/VRSA VANs. Resistance mechanism Penicillin Binding Protein (PBP).

1.17k views • 71 slides

ENTEROBATTERI RESISTENTI AI CARBAPENEMI (CRE) E NUOVI ANTIBIOTICI

544 views • 52 slides

Antibiotics

1.09k views • 49 slides

Antibiotics

735 views • 49 slides

Diagnosis and Management of Sepsis 2013

Diagnosis and Management of Sepsis 2013. Edward L. Goodman, MD Core Faculty Hospital Epidemiologist June 27, 2013. Outline. Recognition and Impact Grades of recommendations Non-antimicrobial management Antimicrobial management Infection Prevention Antibiotic Stewardship.

652 views • 47 slides

Cephalosporin Resist ant Escherichia coli

Cephalosporin Resist ant Escherichia coli. Dr.T.V.Rao MD. Penicillins Ampicillin Amoxicillin Piperacillin Cephalosporins (generations) 1 st gen: cephalothin 2 nd gen (Cephamycins): cefoxitin, cefotetan 3 rd gen: ceftazidime, cefotaxime, ceftriaxone 4 th gen: cefepime.

555 views • 46 slides

Introduction to Antibacterial Therapy

Introduction to Antibacterial Therapy. Clinically Relevant Microbiology and Antibiotic Use Edward L. Goodman, MD July 22, 2010. Outline . Basic Clinical Bacteriology Antibiotics Categories Pharmacology Mechanisms of Resistance.

594 views • 46 slides

The Beta- Lactamase Family: Classification, Detection, and Interpretive Criteria

The Beta- Lactamase Family: Classification, Detection, and Interpretive Criteria. COL Helen Viscount, PhD, D(ABMM) LTC Steven Mahlen, PhD, D(ABMM). Transplant patient. Extremely resistant Klebsiella pneumoniae recovered Sensitive only to colistin and gentamicin Patient put in isolation

1.17k views • 45 slides

Beta-Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors

Beta-Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors. Haitham Mahmood Alwali Ph.D. Pharmacology & Therapeutics College of Medicine/Al- Nahrain University. Penicillins and cephalosporins are the major antibiotics that inhibit bacterial cell wall synthesis.

409 views • 34 slides

Beta-lactam antibiotics Penicillins Target - Cell wall - interfere with cross linking

Beta-lactam antibiotics Penicillins Target - Cell wall - interfere with cross linking Actively growing cells Bind to Penicillin Binding Proteins Enzymes involved in cell wall synthesis. Activity of an Antibiotic Affinity for target Permeability properties

500 views • 29 slides

Plasmid mediated Metallo-Beta-Lactamase (MBL) Plasmid mediated

Plasmid mediated Metallo-Beta-Lactamase (MBL) Plasmid mediated Hydrolyses all beta-lactam (except aztreonam) Inhibited by EDTA Binds zinc (Zn 2+ ) Pseudomonas aeruginosa or Enterobacteriaceae.

242 views • 6 slides