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COX-2 CV Safety valdecoxib-parecoxib

COX-2 CV Safety valdecoxib-parecoxib. James Witter MD, PhD DAAODP/ODE V February 16, 2005. Bextra (valdecoxib). Original NDA (January 15, 2001) 60 studies Phase 1-2: 31 studies Arthritis (OA/RA): 10 studies Included open-label exposure Post-surgical analgesia: 19 studies CABG 035

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COX-2 CV Safety valdecoxib-parecoxib