'Genomic control' presentation slideshows

Peter Kraft pkraft@hsph.harvard Bldg 2 Rm 207 2-4271

957 views • 79 slides

Population Stratification

837 views • 48 slides

Improving Reporting of Association Study Results Timothy R. Rebbeck, Ph.D. University of Pennsylvania School of Medicin

Improving Reporting of Association Study Results Timothy R. Rebbeck, Ph.D. University of Pennsylvania School of Medicine Reporting Genetic Associations Appropriate Study Design? Biological Model? Statistical Analysis? Laboratory QC? Race/Ethnicity? Biological Plausibility?

704 views • 28 slides

On genome-wide association studies (GWAS)

On genome-wide association studies (GWAS). association linkage disequilibrium population structure. case/control design single nucleotide polymorphism data. TTCAGTCAGATCC T AGCCC. Chromosome 1. TTCAGTCAGATCC C AGCCC. Chromosome 2. AAGTCAGTCTAGG G TCGGG. SNP. AAGTCAGTCTAGG A TCGGG.

528 views • 25 slides

Population stratification

Population stratification. Background & PLINK practical. Variation between, within populations. Any two humans differ ~0.1% of their genome (1 in ~1000bp) ~8% of this variation is accounted for by the major continental racial groups Majority of variation is within group

391 views • 22 slides

Population stratification

Population stratification. Background & PLINK practical. Variation between, within populations. Any two humans differ ~0.1% of their genome (1 in ~1000bp) ~8% of this variation is accounted for by the major continental racial groups Majority of variation is within group

573 views • 22 slides