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Colitis reducing effects of Lactobacillus plantarum YS-4 in dextran sulfate sodium-induced C57BL/6J mice

This study observed the inhibitory effect of Lactobacillus plantarum YS-4 (LP-YS4) on the colitis through mice colitis which was induced by DDS (Dextran Sulfate Sodium). By observing the colon shape of mice, the test kit and quantitative PCR (polymerase chain reaction) technique were used to detect the mice, and the effect of LP-YS4 was compared with the positive control of drug sulfasalazine. The results showed that LP-YS4 can increase the colon length of colitis mice and improve the ratio of colon weight/ colon length.

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