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These methods take advantage of large 1 J coupling constants

The number of protons yielding correlations in a 2D NOESY spectrum quickly overwhelms the space available on A 2D map. 15N labeling can help simplify the fingerprint region but not the aliphatic region. These methods take advantage of large 1 J coupling constants.

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Proton 90o - PowerPoint PPT Presentation

These methods take advantage of large 1 J coupling constants