'Rmsd' presentation slideshows

Structure Alignment

Structure Alignment. Structure Alignment. +. Content. Motivation Some basics Double Dynamic Programming. PART I: Motivation. Motivation: Conformational changes. Upon ligand binding structures may change Structural alignment can highlight the changes. GEFs. GAPs.

819 views • 63 slides

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978 views • 58 slides

Prediction of Protein Structure and Function on a Proteomic Scale

Prediction of Protein Structure and Function on a Proteomic Scale. Jeff Skolnick Director Center of Excellence in Bioinformatics. General Approach. Prediction of Protein Structure. Overview of CASP5 Results:. Comparative Modeling (CM) Results. T0153 CM.

546 views • 54 slides

Conformational Space

Conformational Space. Conformational Space. Conformation of a molecule: specification of the relative positions of all atoms in 3D-space, Typical parameterizations : List of coordinates of atom centers List of torsional angles (e.g., the f - y - c for a protein)

734 views • 48 slides

Sequence Homology Treat or Trick?

440 views • 28 slides

Protein Structure Alignment

Sequence id: 27% Structural id: 90%. Protein Structure Alignment. Human Hemoglobin alpha-chain pdb:1jebA. Human Myoglobin pdb:2mm1. Another example: G-Proteins: 1c1y:A, 1kk1:A6-200 Sequence id: 18% Structural id: 72%. Transformations. Translation Translation and Rotation

226 views • 19 slides