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TACTICS-TIMI 18

TACTICS-TIMI 18. T reat Angina with A ggrastat + Determine C ost of T herapy with an I nvasive or C onservative S trategy TIMI 18. As presented by Dr. Cannon at AHA 2000. Background and Hypothesis. Unstable angina and non-ST elevation MI: 1.3 million admissions/yr in U.S.A.

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732 views • 34 slides

IV Heparin, (ASA), Beta-blockers, Nitrates, Ca ++ blockers

TIMI IIIA. Protocol Design. 391 Patients with Unstable Angina / NQWMI. IV Heparin, (ASA), Beta-blockers, Nitrates, Ca ++ blockers. Angio Exclusion: no CAD or LMain. Baseline Angio. Randomize. Placebo. t-PA 0.8 mg/kg over 90 mins. Primary Endpoint: Death, MI, Positive ETT 6 weeks.

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297 views • 8 slides

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TACTICS-TIMI 18

IV Heparin, (ASA), Beta-blockers, Nitrates, Ca ++ blockers