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Definition. Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure greater than 25 mmHg at rest or 30 mmHg with exercise, as measured by right heart catheterization. Classification. Initially classified as idiopathic and secondary pulmonary hypertensionWHO classificationGroup
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1. Pulmonary Hypertension Jennifer O’Brien
November 14, 2008
2. Definition Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure greater than 25 mmHg at rest or 30 mmHg with exercise, as measured by right heart catheterization
3. Classification Initially classified as idiopathic and secondary pulmonary hypertension
WHO classification
Group 1: Pulmonary arterial hypertension
sporadic idiopathic PAH, familial IPAH, collagen vascular diseases (scleroderma, RA, SLE), congenital heart disease, HIV, Appetite suppressants, stimulants
4. Classification Group 2: Left heart failure
Left atrial, ventricular or valvular disease
Group 3: Hypoxemia, respiratory disease
COPD, Sleep disorders, alveolar hypoventilation
Group 4: Chronic thrombotic, embolic dx
Group 5: inflammation, mechanical obstruction, extrinsic compression
sarcoid, histoiocytosis, fibrosing mediastinitis, pulmonary venous obstruction
5. Signs and symptoms Exertional dyspnea, lethargy and fatigue
Chest pain, exertional syncope, peripheral edema due to right heart failure
Anorexia, abdominal pain (RUQ) due to hepatic congestion
Cough, hemoptysis, hoarseness due to compression of L recurrent laryngeal nerve
6. Diagnosis Goal: Determine it patient has pulmonary hypertension and determine underlying cause