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coagulopathy made easy. Dr.Ali Ahmad KBA PGY2. the pathways. high ptt . Heparin effect The Correction The Inhibitor effect . causes of high ptt . DIC heparin therapy factors deficiencies ( 11.10.9.8 ) inhibitors such as LA . ACL . VWD .hemophilia . . high PT and INR .
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coagulopathy made easy • Dr.Ali Ahmad KBA PGY2
high ptt • Heparin effect • The Correction • The Inhibitor effect
causes of high ptt • DIC • heparin therapy • factors deficiencies ( 11.10.9.8 ) • inhibitors such as LA . ACL . • VWD .hemophilia .
high PT and INR • warfarin therapy • factors dependent of vit K • liver • DIC
clinical scenario • 30 y old male obese known to have thrombosis with PE on warfarin . admitted due to mild bleeding per rectum .
my anticoagulated pt is bleeding • HASHTI . • 1-Hold • 2-Antidote • 3-Support • 4-Hemostatic measures • 5-Transfusion • 6-Investigate • level of urgency .
antidotes high PT hi • vit K • FFP • prothrombin complex concentrates • recombinant factor 7
clinical scenario • 46 years old pt taking clexane for DVT prophylaxis . know D/A admitted with LL fracture need urgent surgery .
antidotes • protamine sulfate . • Fresh frozen plasma .
THANKS • God bless medicine • So others may live