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Type I errors Purcell model

Type I errors Purcell model. If M and T are correlated (eg via A), and M is correlated between twins as well, then the original specification of the Purcell moderation model can yield a large number of false positives. Slides: S van der Sluis, VU University Amsterdam.

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Type I errors Purcell model

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  1. Type I errors Purcell model If M and T are correlated (eg via A), and M is correlated between twins as well, then the original specification of the Purcell moderation model can yield a large number of false positives Slides: S van der Sluis, VU University Amsterdam

  2. Results simulation study type I error M and T correlated via A Type I increased for Ba and Bc M and T correlated via C Type I increased for Ba and Bc M and T correlated via E Type I increased for Ba, Bc and Be Slides: S van der Sluis, VU University Amsterdam

  3. Extension means model Original model Extension means model Slides: S van der Sluis, VU University Amsterdam

  4. Unless… Unless the covariance between M and T is subject to moderation as well. Then the univariate parameterization should not be used (again increased false positive rate) Slides: S van der Sluis, VU University Amsterdam

  5. Conclusion • Always first fit the bivariate • moderation model. • 2. If moderation on covariance M and T is present: • stick to bivariate moderation model • 3. If moderation on covariance M and T is absent: • proceed with extended univariate parameterization (more powerful!) Slides: S van der Sluis, VU University Amsterdam

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