1 / 16

Netherlands Twin Register (NTR)

Seventeenth International Workshop On Methodology of Twin And Family Studies. Boulder, CO, 2004. Netherlands Twin Register (NTR). 30,000 twin pairs registered at birth, born after 1986. Questionnaire variables Zygosity, health and growth 2, 3, 5, 7, 10, 12, (14, 16)

ted
Download Presentation

Netherlands Twin Register (NTR)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Netherlands Twin Register (NTR) 30,000 twin pairs registered at birth, born after 1986 Questionnaire variables Zygosity, health and growth 2, 3, 5, 7, 10, 12, (14, 16) SES 3, 7, 10, 12 Problem behavior CBCL (Devereux at 5) 3, 5, 7, 10, 12 TRF 7, 10, 12 YSR 12, (14, 16) Motor development 2, 5 School achievement 5, 12, (14, 16) Family Composition 5, 12, (14, 16)

  2. Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Aggressive and Rule-Breaking Behavior

  3. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Aggressive Behavior 10 year old twins rated by their mother skewness: 1.346

  4. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Square root transformed Aggressive Behavior 10 year old twins rated by their mother skewness: .046

  5. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 SPSS descriptives Pairs Ma Mb Vara Varb r MZM 514 2.41 2.38 1.62 1.56 .84 DZM 467 2.24 2.31 1.62 1.50 .50 MZF 609 1.98 1.90 1.31 1.28 .79 DZF 452 1.95 1.91 1.36 1.26 .54 DOSm-f 8852.23 1.811.57 1.29.47

  6. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Mx Means and Variance (Saturated) Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Males-2LLdfparΔχ2dfpAIC means free 5712.15 1956 10 eq means 5716.90 1959 7 4.755 3 .191 -1.245 eq m/ eq v 5718.77 1962 4 6.622 6 .357 -5.378 Females-2LLdfparΔχ2dfpAIC means free 5844.97 2120 10 eq means 5854.08 2123 7 9.110 3 .028 3.11 eq m/ eq v 5855.33 2126 4 10.360 6 0.110 -1.64 eq v 5846.23 2123 7 1.257 3 0.139 -4.74

  7. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Mx Estimates of Means and Variances T1 T2 VT1 VT2 r r (eq m) MZF 1.99 1.90 1.31 1.28 .792 .789 DZF 1.95 1.91 1.36 1.26 .538 .537 MZM 2.41 2.38 1.61 1.56 .83 .838 DZM 2.24 2.30 1.61 1.49 .50 .499

  8. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Practical Test Means and Variance in 4 group script F:\ meike\ uni example \ satm.mx • Create a 4 group script with males and females • test means and variances

  9. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Mx Means 4 groups Males/Females-2LLdfχ2dfpAIC eqmm eqmf 11574.103 4088 mm = mf11639.178 4089 65.075 1 .00 63.075 eqvar 11586.696 4089 12.591 1 .00 10.593

  10. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Model Fitting Results Boys -2LL df χ2 df p AIC ACE 5718.768 1962 AE 5724.465 1963 5.696 1 .017 3.696 CE 5869.551 1962 150.78 1 .00 148.783 A= .67 C=.17 E=.16 Girls -2LL df χ2Δdf p AIC ACE 5855.335 2126 AE 5870.988 2127 15.65 1 .00 13.65 CE 5942.60 2127 87.26 1 .00 85.265 A= .52 C=.28 E=.20

  11. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Mx Practical ACE model for 4 groups F:\meike\uni example\unim.mx Create a 4 group script with males and females Estimate A, C. and E

  12. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 4 group analysis -2LL df χ2 df p AIC ACE 11574.103 4088 ACEnsd 11591.813 4091 17713 3 .001 11.710 Boys 5718.768 1962 Girls 5855.335 2126 Am Af Cm Cf Em Ef ACE .67 .52 .17 .28 .16 .20 (.54-.81) (.40-.65) (.03-.29) (.15-.39) (.14-.19) (.18-.23) ACEnsd .60 .22 .18 (.51-.69) (.12-.30) (.17-.20)

  13. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Mx Means SS and OS twins (5 groups) Males-2LLdfχ2dfpAIC ss ≠ os 17011.614 5851 ss= os 17015.035 5852 3.42 1 .06 1.421 Mean SS = 2.33 Mean OS = 2.23 Females-2LLdfχ2dfpAIC ss ≠ os 17011.614 5851 ss= os 17042.096 5852 30.48 1 .00 28.482 Mean SS = 1.94 Mean OS = 1.81

  14. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 The Opposite sex group Open unimfh_5groups

  15. Table 1: CBCL-items of the syndrome Aggressive Behavior for the CBCL/2-3 and CBCL/4-18 Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 5 group analysis -2LL df χ2 df p AIC Hfree 14229.726 4986 Hfixed .5 14229.726 4987 0 1 -2.00 ACEnsd 14246.423 4990 16.696 4 .002 8.696 Estimate H=.5 (.42-.50)

  16. Seventeenth International Workshop On Methodology of Twin And Family Studies Boulder, CO, 2004 Estimates of variance components 2groups 4 groups 5 groups Am .67 .67 (.54-.81) .63 (.53-.72) Af .52 .52 (.40-.65) .50 (.39-.62) Cm .17 .17 (.03-.29) .20 (.11- .30) Cf .28 .28 (.15-.39) .29 (.18-.40) Em .16.16 (.14-.19) .17 (.15-.19) Ef .21 .20 (.18-.23) .21 (.18-.23)

More Related