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Fasciola Hepatica

Fasciola Hepatica. Amy Liberio Heather Peters. Fasciola hepatica. One of the world’s largest fluke Worm: 30 mm x 13 mm Distinguishable from other faciolidae by: Oral cone “Shoulders” Widening of body at base of oral cone Highly branched ceca. Geographical Distribution.

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Fasciola Hepatica

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  1. Fasciola Hepatica Amy Liberio Heather Peters

  2. Fasciola hepatica • One of the world’s largest fluke • Worm: 30 mm x 13 mm • Distinguishable from other faciolidae by: • Oral cone • “Shoulders” • Widening of body at base of oral cone • Highly branched ceca

  3. Geographical Distribution • Worldwide (excluding Antarctica) • Where sheep or cattle are raised

  4. Hosts • Definitive host: sheep, cattle • Accidental host: humans • Intermediate hosts: snails

  5. Morphological Forms • Fluke (worm) • Eggs • Micracidium • Sporocyst • Rediae • Cercariae • Metacercaria • Hermaphroditic

  6. Life Cycle

  7. Life Cycle • Metacercariae ingested • Young flukes released from cyst in digestive tract • Adult fluke moves to bile ducts • Eggs are released and passed in feces • Eggs develop in water and hatch miracidium • Miracidium penetrates snail • Mother sporocyst produce daughter rediae • Daughter rediae produce cercariae • Cercariae released in water • Cercariaeencyst and become metacercariae

  8. Infection and Signs • Symptoms: • Gastrointestinal problems: • Nausea • Vomiting • Abdominal pain/tenderness • Fever • Rash • Difficulty breathing • Anemia • Migrating juveniles can produce ulcers in eyes, brain, skin and lungs • Can eventually lead to Fascioliasis

  9. Diagnosis and Treatment • Diagnosis: • Eggs in stool sample (after a few months) • Enzyme-linked immunosorbent assay (ELISA) • Antibodies in blood sample • Treatment: • Prescription drugs • Rafoxanide • Trichlabendazole • No vaccine

  10. Economic importance • Huge issue in cattle and sheep industries • Lowered productivity • Lowered fertility • Lowered quality of animal products

  11. Prevention & Control • Control growth and sale of watercress and other water plants • Avoid potentially contaminated water and/or food • Cook vegetables well that were possibly grown with contaminated water

  12. Review • What is a definitive host for F. Hepatica? • What are a few symptoms? • What morphological form is considered infective? • What is one way to prevent infection?

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