AfCS-Nature Molecule Pages: The AfCS M&E Office Perspective

1. AfCS-Nature Molecule Pages:The AfCS M&E Office Perspective Patrick J Casey

2. The AfCS M&E Office Team • Sharon Brown, Staff Assistant/Office Manager • Ashley Butler Brossoie, Scientific Editor • AfCS/Nature Editorial Board (25+ members) Based at Duke University in the Heart of Carolina

3. The M&E Office Management Sharon Brown • Correspondence with Members • Issue author invitations • Maintain registration records, • Maintain historical data • Answer queries • Molecule Pages • Track authorship • Communicate with Editorial Board • Protein List • Add new proteins • Maintain synonyms lists

4. Scientific Editing at AfCSAshley Butler Brossoie • Reports, Protocols • Edit AfCS reports • Edit procedure, solution, and ligand protocols • Create/update protocol templates and style guide • Molecule Pages • Initial assessment of MPs • Final edit of MPs • Edit/review MP instructions, letters, templates, and tools

5. Molecule Pages Database • Contains 3,800 molecules at present • 1600+ have assigned authors • 800+ authors • New molecules added through many routes • Editorial Board recommendations • AfCS lab/committee recommendations • AfCS Member recommendations • Recommendations from scientists through Signaling Gateway Web site

7. Past and Future Goals of the M&E Office • Goal for 2003 - 2004 • Publish the first full Molecule Pages • Goal for 2004 - 2005 • Publish a whole lot more Molecule Pages

8. Potential Impediment to Our Goal • Many authors committed years ago to effort; would they still participate?

9. Potential Impediments to Our Goal • Many authors committed years ago to effort; would they still participate? SolutionFormal re-invitation from NPG

14. Magic Button

15. London/NPG Duke Editorial board Authors Referees San Diego AfCS/Nature Editorial Process hosting

16. AFCS/Nature Editorial Board Pat Casey, Duke (Chair) Ken Harden, UNC-Chapel Hill (Vice Chair) GPCRs Joe Albanesi, UT-Southwestern Myosins/cytoskeletal Cathy Berlot, Weis Institute G proteins and effectors Michael Brownstein, NIH GPCRs Bill Catterall, Univ. of Washington Ion channels Paul Dawson, Wake Forest Transporters Michael Dean, NCI ABC transporters Haian Fu, Emory Phosphoprotein binding partners James Garrison, Univ. of Virginia G protein β, γ subunits and targets Michael Graziano, Schering Plough GPCRs Donald Gullberg, Univ. of Bergen Integrins, laminins, cell surface Robin Irvine, Cambridge PI-metabolizing enzymes Jack Keene, Duke RNA binding proteins John Kyriakis, Harvard Protein kinases Maurine Linder, Wash. U. Lipid modification/trafficking Randy Moon, Univ. of Washington Wnt/Frizled pathway Mary Moore, Baylor Nuclear import Ben Neel, Harvard Protein phosphatases Leslie Parise, UNC-Chapel Hill Integrins Richard Premont, Duke Targets of small G proteins David Siderovski, UNC-Chapel Hill RGS proteins and regulators Jeremy Thorner, UC-Berkeley Intracellular kinases and signaling Michael White, UT-Southwestern Ras/Rac/Rho/Rap Tom Wilkie, UT-Southwestern Target of heterotrimeric G proteins

17. Ed. Board Author contract London/NPG Duke Duke Authors Authors Referees San Diego Editorial Workflow Duke Invitation submission verification confirmation chasing Editorial Board conflict resolution accepted MP revision peer review subediting Annual revision & peer review posting

18. The AfCS Membership and Editorial OfficeWe’re there for you!

19. The AfCS Membership and Editorial Office We’re there for you!