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Sickle Cell Anemia

Sickle Cell Anemia. Chisom Amaefuna Adeline Laurente 1/29/10 Period 2. Summary. Sickle Cell Anemia is a Genetic Blood DISEASE DUE TO A Abnormal form of a Hemoglobin. Hemoglobin is the molecule in the red Blood cell that transports Oxygen from lungs to the farthest parts of the body

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Sickle Cell Anemia

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  1. Sickle Cell Anemia Chisom Amaefuna Adeline Laurente 1/29/10 Period 2

  2. Summary Sickle Cell Anemia is a Genetic Blood DISEASE DUE TO A Abnormal form of a Hemoglobin. Hemoglobin is the molecule in the red Blood cell that transports Oxygen from lungs to the farthest parts of the body Symptoms of Sickle Cell Anemia include: Paleness of the Skin Weakness Shortness of Breath Heart Failure Fact: Couples who are both carriers can

  3. Chromosomes Sickle Cell Anemia is located in CHROMOSOME 11

  4. Inheritance of Sickle Cell Anemia -Sickle cell is inherited in an Autosomal recessivepattern. -autosomal recessive-Genetic condition that appears only in individuals who have received two copies of an autosomal Gene -The gene is on an autosome, a nonsex chromosome -People with one defective gene and one normal gene are carriers

  5. Alleles

  6. Punnett squares

  7. Probability of Punnett squares RATIOS PERCENTAGES 25% SS: 50% Ss: 25% ss S s S SS Ss s Ss ss

  8. Genotype and Phenotype GENOTYPE What is in the GENES S represents dominant allele GREEN s represents recessive allele yellow SS=homozygous dominant (GREEN) Ss= heterozygous dominant (GREEN) ss= homozygous recessive (yellow) 25%: 50% : 25% Normal to carrier to affected PHENOTYPE What you can SEE SS= GREEN Ss= Green (yellow gene carrier) Ss= yellow 3:1 Normal to affected

  9. Genotype and Phenotype Probablilty

  10. Student Practice with Punnett Squares

  11. Pedigree KEY CIRCLE- FEMALE SQUARE- male White- normal Red-affected HALF- CARRIER

  12. Student Practice with Pedigree KEY CIRCLE- FEMALE SQUARE- male White- normal Red-affected HALF- CARRIER

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