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Unit One

Unit One. – Introduction to Laboratory Animal Care. Chapter one. The Field of Laboratory Animal Science. Laboratory Animal Science. Care of laboratory animals husbandry nutrition behavior health production management. Laboratory Medicine.

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Unit One

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  1. Unit One – Introduction to Laboratory Animal Care WIL Research Laboratories, LLC

  2. Chapter one The Field of Laboratory Animal Science WIL Research Laboratories, LLC

  3. Laboratory Animal Science • Care of laboratory animals • husbandry • nutrition • behavior • health • production • management WIL Research Laboratories, LLC

  4. Laboratory Medicine • diagnosis, treatment and prevention of laboratory animal disease • veterinary specialty WIL Research Laboratories, LLC

  5. Role of Technician • eyes, ears, hands of the team that provides information from the animals to the investigator. WIL Research Laboratories, LLC

  6. Laboratory Animal Science • recognized field in late 1940’s • animals used in experimentation • Aristotle • 2nd century Rome • advances into early 20th century • 1915- Simon Brimhall (first laboratory animal veterinarian) • 1950’s- humane awareness of animals in research, more government funding, public concern WIL Research Laboratories, LLC

  7. Animal Care Panel • Group of Veterinarians • Lead by Dr. Nathan Brewer • 1950 • Goal to create a national organization professionally concerned with the production , care, and study of laboratory animals. WIL Research Laboratories, LLC

  8. Animal Care Panel • Basic philosophy: Those who use animals for research have a moral obligation to provide for their needs and ensure their welfare. • Defined good husbandry practices • Defined medical care needs • became American Association for Laboratory Animal Science (AALAS) in 1967 WIL Research Laboratories, LLC

  9. AALAS • National organization dedicated to the humane care and treatment of lab animals • two journals • Journal of AALAS • Comparative Medicine • certifies technicians • promotes education • Annual meetings WIL Research Laboratories, LLC

  10. Other Associations • AAALAC • Association for the Assessment and Accreditation of Laboratory Animal Care, International • Formed in 1965 • voluntary site evaluations and accreditation • high standards • WIL is accredited WIL Research Laboratories, LLC

  11. Other Associations • National Association for Biomedical Research (NABR) • Incurably Ill for Animal Research (iiFAR) • American Veterinary Medical Association (AVMA) • 2000 Report of the AVMA Panel on Euthanasia • veterinarians WIL Research Laboratories, LLC

  12. More…... • American College of Laboratory Animal Medicine (ACLAM) • board certified veterinarians (called Diplomats) • Specialize in Lab animal medicine, completion of examination, etc. WIL Research Laboratories, LLC

  13. Animal Models • Similar processes • Nervous system development – zebrafish • Brain development – monkeys • Heart – pig • Many medical and surgical advances WIL Research Laboratories, LLC

  14. Differing views • People for the Ethical Treatment of Animals (PETA) • Stop Huntington Animal Cruelty USA • opposed to the use of animals in research • Distribute pamphlets • demonstrations WIL Research Laboratories, LLC

  15. Research team • Principle investigator/study director • Co-investigators and Research Technicians • Technicians • Veterinarian • Commercial vendors

  16. Principal Investigator • PI, Study director • Plans and coordinates all phases of the research work • Develops the Protocol • Reports findings WIL Research Laboratories, LLC

  17. Co-investigators and Research technicians • Observing the experimental animals • Performing laboratory tests • Collect, organize, and analyze the data • Can be animal technicians WIL Research Laboratories, LLC

  18. Laboratory Animal Veterinarians • Coordinate animal care activities • Advises investigators on proper animal model selection • Overall maintenance of animal colony health • Assure compliance with various regulations WIL Research Laboratories, LLC

  19. Laboratory Animal Technicians • reduce variables • environment, handling, etc • provide consistent and thorough animal care • first to recognize and report potential animal problems • should have general knowledge of regulations concerning animal use in research WIL Research Laboratories, LLC

  20. Roles continued... • keep accurate records • accurate, legible • Willing to learn about the animals in their care • Follow SOPs • always ask if in DOUBT! WIL Research Laboratories, LLC

  21. Certifications • Through AALAS • Assistant Laboratory Animal Technician (ALAT) • Laboratory Animal Technician (LAT) • Laboratory Animal Technologist (LATG) WIL Research Laboratories, LLC

  22. ALATs should be able to: • Handle routine husbandry tasks – watering, feeding, bedding changes • Perform sterilization and sanitation procedures • Observe and report environmental changes • Handle, restrain, and determine sex of common lab animals WIL Research Laboratories, LLC

  23. Cont' • Use a variety of methods of animal identification • Recordkeeping • Recognize common signs of illness, note changes in eating, behavior, stool or urine • Provide routine treatments, such as administering medications or clipping overgrown toenails WIL Research Laboratories, LLC

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