Figure S1. Lee et al .

Figure S1. Lee et al. 16 LL-37 A B 12 8 4 Mabc Relative mRNA expression DEFB4 20 (h) 0 3 6 18 48 15 LL-37 10 5 DEFB4 0 -actin 0 3 6 18 48 (h) Mabc 20 IL-1 IC α-Dectin-1 15 U M U M 10 IL-1 5 LL-37 LL-37 16 DEFB4 12 Relative mRNA expression -actin 8 4 20 DEFB4 15 10 5 0 U M U M α-Dectin-1 IC

8 Casp1 p10/ -actin 6 ┏ ┏ SN Cell 4 2 50 kD Figure S2. Lee et al. 35 kD 8 35 kD 6 IL-1 p17/ -actin Mabc 4 24 kD 2 PIC USC 0 USC PIC Casp1 A B Mabc pro-IL-1 -actin Casp1 p10 15 kD IL-1 p17 7 kD 20 kD 15 kD 1600 1200 800 TNF-α (pg/ml) 400 0 USC PIC Mabc

Figure S3. Lee et al. A B C ┏ ┏ SN Cell 50 kD 280 Mabc 35 kD sip62 siNS None 210 (h) 0 3 6 18 48 35 kD p62 p62 IL-1 (ng/ml) 140 24 kD *** -actin -actin 70 0 U M U M UM siNS sip62 sip62 siNS U M U M U M Casp1 pro-IL-1 8 Casp1 p10/ -actin 6 15 kD -actin 4 7 kD 2 Casp1 p10 8 6 IL-1 p17/ -actin 20 kD 4 IL-1 p17 2 15 kD 0 U M U M U M siNS sip62

Figure S4. Lee et al. shNS siNS sip62 shp62 120 sip62 80 Cell viability (%) 40 0 120 shp62 80 40 0 0 6 12 24 (h)

Figure S5. Lee et al. A B C ATP nigericin (h) 0 3 6 18 48 0 3 6 18 48 (h) p62 -actin shNS shp62 UANUANUAN IL-1β p62 -actin 280 210 140 IL-1 (ng/ml) 70 0 U A N U A N U A N shNS shp62

Figure S1. Lee et al .

Figure S1. Lee et al .

Presentation Transcript

Lim et al, Supplemental Figure S1.

Hwang et al., Figure S1

Sul et al, Supplementary Figure S1.

Figure S1, Birtwistle et al.

Supplementary Figure S1 Wang et. al.

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Figure S1, Ferreira et al.

Kuwano et al., Supplemental Figure S1