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Finding High Level Evidence in PubMed

Finding High Level Evidence in PubMed. Presented by Erin O’Toole erinmotoole@gmail.com. Objectives. Become familiar with: The types of higher level evidence publications Why you would want to use PubMed The content of PubMed MeSH = Medical Subject Headings

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Finding High Level Evidence in PubMed

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  1. Finding High Level Evidence in PubMed Presented by Erin O’Toole erinmotoole@gmail.com

  2. Objectives • Become familiar with: • The types of higher level evidence publications • Why you would want to use PubMed • The content of PubMed • MeSH = Medical Subject Headings • Two ways to search for higher level evidence

  3. Levels of Evidence Randomized Controlled Trials = RCTs Systematic Reviews/ Meta-analyses of RCTs LEVEL1 LEVEL 2 Individual RCTs Mechanism-based Reasoning LEVEL 5 Adapted from "The Oxford Levels of Evidence 2". Oxford Centre for Evidence-Based Medicine. http://www.cebm.net/index.aspx?o=5653

  4. Why Use PubMed? • Not all systematic reviews are published in EBM resources. • It’s FREE! • You won’t be at UT Southwestern forever. • Loansome Doc service • Produced by National Library of Medicine

  5. What’s in PubMed? • MEDLINE – index and abstract of 5600 biomedical journals • index = citation and MeSH for article • abstract = summary of article • Books and book chapters from NCBI Books • Articles from PubMed Central Over 22 MILLION article records in PubMed!

  6. Beware the Basic Search Ratio of systematic reviews to case reports?

  7. PubMed Tool: Clinical Queries • Includes search limited to systematic reviews, meta-analyses, and other high-level evidence • But wait . . . • Limited to specific clinical research areas • Not all topics covered • No economic analyses • Comprehensive search has to be done directly in PubMed

  8. Search with MeSH • Medical Subject Headings • “Tags” assigned to articles to describe their content • 16 categories of terms, general to specific • Automatically EXPLODES your search

  9. A live demonstration of searching for high level evidence in PubMed occurred at this point in the presentation.

  10. References Heneghan, Carl, and Douglas Badenoch. Evidenced-Based Medicine Toolkit, 2nd ed., Maiden, Mass.: BMJ Books/Blackwell Pub., 2006. OCEBM Levels of Evidence Working Group. "The Oxford Levels of Evidence 2". Oxford Centre for Evidence-Based Medicine. http://www.cebm.net/index.aspx?o=5653 QUESTIONS? Erin O’Toole erinmotoole@gmail.com

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