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Goldman Sachs Healthcare Conference 2008 ICON Plc. Peter Gray, CEO

Goldman Sachs Healthcare Conference 2008 ICON Plc. Peter Gray, CEO. Forward Looking Statements.

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Goldman Sachs Healthcare Conference 2008 ICON Plc. Peter Gray, CEO

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  1. Goldman Sachs Healthcare Conference 2008 ICON Plc.Peter Gray, CEO

  2. Forward Looking Statements Certain statements contained herein including, without limitation, statements containing the words “believes,” “anticipates,” “intends,” “expects” and words of similar import, constitute forward-looking statements concerning the Company's operations, performance, financial condition and prospects. Because such statements involve known and unknown risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Given these uncertainties, prospective investors are cautioned not to place undue reliance on such forward-looking statements. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

  3. Global Full Service Clinical Development Platform…. • 6300 staff in • 69 Offices in • 37 Countries EU 38% Q1 Activity by Region ROW 9% US 53%

  4. ..in a Strong Market Environment… • Continued R&D Spending Growth. • Phase II / III pipelines strengthening • Scientific innovation continues to expand • Increased Outsourcing • Globalisation of clinical research • New strategic thinking / cost containment • More virtual / small companies • Increasing Regulation • More patients/ more studies • Post marketing surveillance 5

  5. .. Delivering excellent Net New Business wins and very strong book to bill ratios… Net Business Wins Book to Bill Ratio

  6. …leading to record Total Backlog levels. ($ millions) Up 54% YoY Up 23% YoY

  7. This has driven industry leading Revenue growth… Forecast 35% CAGR 33% *Mid Point of 2008 Guidance issued April, 2008

  8. …and strong Earnings Per Share growth. CAGR 27% (E) *Mid Point of 2008 Guidance issued April 2008

  9. Margin improvement is a key focus. • Approx. 25% of ICON’s business is generating single digit margins • Further margin growth in Lab • Improve performance from Phase I and Consultancy businesses • Expand margins in Phase II – IV through leverage as growth moderates. • Currency Movements creating significant “Headwinds” 5

  10. Investment Case Summary • Top Global Clinical CRO - #4 • Outstanding record of growth • Strong market fundamentals • Excellent strategic position • Strong balance sheet • Margin expansion opportunity

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