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Forensic DNA Analysis

Forensic DNA Analysis. Microarrays In Action. Forensic DNA Analysis. Every cell in our body contains a copy of our DNA. Our DNA can be uniquely identified in a test called the Southern Blot. DNA in CSI. Every Base Matters.

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Forensic DNA Analysis

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  1. Forensic DNA Analysis Microarrays In Action

  2. Forensic DNA Analysis Every cell in our body contains a copy of our DNA. Our DNA can be uniquely identified in a test called the Southern Blot.

  3. DNA in CSI

  4. Every Base Matters Changing just one letter in a word changes its meaning. By changing just one letter, ‘match’ can become ‘catch’, ‘patch’ or ‘batch’. Changing just one base in a gene can change things like the color of our eyes or hair. One gene, called the bey2 gene, effects our eye color. Changing just one base can change our eyes from brown to blue.

  5. Other Traits Cleft Chin Widow’s Peak Dimples Earlobes

  6. Anatomy of a Gene

  7. Hair Color Blonde Red Brown Black

  8. Eye Color Blue Green Brown

  9. Microarray • Microarrays can test 10,000 genes at a time, with each gene attached to a specific site in the array. They laser reads the array and the results are analyzed by computer.

  10. Microarray Brown Green Blue Widow’s Peak Cleft Female No Cleft No Peak Male

  11. Build Your Microarray Green Brown Blue Widow’s Peak Female Cleft Male No Cleft No Peak

  12. Using A Microarray • What genes does the suspect have? How do you know? • Why does one side of a gene only match up with their partner? • Who does your microarray implicate? How do you know? • Why would a real microarray, with the real procedure, be more accurate than what we did?

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