CBET Mission:  Support Research in Chemical, Bioengineering, Environmental, & Transport Systems

1. Chemical, Bioengineering, Environmental, and Transport Systems, CBET CBET Mission: Support Research in Chemical, Bioengineering, Environmental, & Transport Systems Catalyze the merging of biology, chemistry, physics and socio-economic science in engineering research Support research to enhance and protect US national health, energy, environment, security and wealth

2. Chemical, Biochemical and Biotechnology Systems Slide 1 of 2 A Synthetic Delivery Vehicle for Gene Transfer  “hitchhike” gene delivery nanoparticles onto motor protein complexes  Convert chemical energy to mechanical work  Carry nanoparticle cargo toward cell nuclei Suzie Pun, U. of Washington

3. Chemical, Biochemical and Biotechnology Systems Slide 2 of 2 • Bloodless Biosensing with Carbon Nanotubes •  Implantable capillary devices • Filled with carbon nanotubes • Monitor glucose levels without drawing blood • For diabetes and other biosensors Michael Strano, UIUC 4 1 2 3 1 Finger Implanted with2 Capillary Tube 3 Non-invasive near-Infrared Image 4 Compare

4. Transport and Thermal Fluids Phenomena Slide 1 of 2 • High-Fidelity Numerical Modeling & Simulation of Fire Suppression  Predicts multiphase turbulent mixing processes over a wide range of time/length scales. •  Grand challenge of turbulence • modeling with reactions •  Multi-scale modeling on • both large and small scales Includes Sandia, Navy & NIST interactions plus excellent educational components. Paul E. DesJardin SUNY Buffalo

5. Transport and Thermal Fluids Phenomena Slide 2 of 2 Nanocolloid Assembly and Dispersion by Quantum “Design” of van der Waals Forces  Nanocolloids have remarkable electrical, optical and reactive properties  Need to prevent aggregation by predicting and controlling van der Waals forces  Use solvent mixtures to “shield” nanocolloids to keep them stable Stable nanoparticles Groups of red atoms with co-solvent “shield” (blue) Darrell Velegol & Milton W. Cole Penn State Unstable (aggregated) particles

6. Biomedical Engineering and Engineering Healthcare Slide 1 of 2 B’Quest Crew Completed 2,500 mile Transpac Yacht Race Each crew member, except the skipper, had a disability Engineering students at San Diego State University designed adaptive equipment on the yacht for crew members with disabilities Michael Lambert, SDSU

7. Biomedical Engineering and Engineering Healthcare Slide 2 of 2 Biomimetic Bone Mimic both composition and nanostructure of bone Prepare synthetic bone prosthetics  Load- bearing Bioresorbable  Enable regeneration of hard tissue prosthetics into natural bone. NIRT: Laurie Gower, Elliot Douglas, & John Mecholsky, University of Florida Barbara Boyan, Georgia Institute of Technology

8. Environmental Engineering and Sustainability Slide 1 of 2 An Autonomous Microbial Genosensor for Freshwater Microbial Ecology  Remote sampling High frequency and high degree of specificity Multi-day deployment in lakes to detect bacteria David FriesWisconsin

9. Environmental Engineering and Sustainability Slide 2 of 2 Aquatic Nano Environmental Heath and Safety of Nanomaterials and Their Bimolecular Derivatives Binding of lysophospholipid onto single-walled single-walled carbon nanotubes (SWNTs) over a silicon substrate Finalist at the Science & Engineering Visualization Challenge 2006 by NSF and the Science magazine. Pu Chun Ke Clemson University

10. CBET Workshops iEngineering approaches to obesity iCyber- based Combustion Science iMinority Faculty Workshop iResearch Frontiers for Combustion in the Hydrogen Economy iWorkshop on Cyberinfrastructure in Chemical & Biological Systems iGrand Challenges of the Future for Environmental Modeling  iA Workshop for integrating Social Sciences Research in the WATERS Network and other Environmental Observatories iFrontiers in Environmental Engineering Education  iSustainable Nanomanufacturing (US/Aus/Singapore)