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GEM Design Gel Extrusion Module

GEM Design Gel Extrusion Module. Drug is compressed with water swellable Carbopol polymer Tablet is coated with water insoluble CAB coating Laser drill drills uniformly sized holes through coating (~500 m ) Water diffuses into tablet, swells polymer, which extrudes through holes, bringing drug

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GEM Design Gel Extrusion Module

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  1. GEM DesignGel Extrusion Module • Drug is compressed with water swellable Carbopol polymer • Tablet is coated with water insoluble CAB coating • Laser drill drills uniformly sized holes through coating (~500m) • Water diffuses into tablet, swells polymer, which extrudes through holes, bringing drug • Release rate is controlled by number, size, configuration of holes • Number of holes constrained by surface area, strength of coating

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