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12-2 Chromosomes and DNA Replication. Pg. 295. A. DNA and Chromosomes. 1. Prokaryotes have no nucleus; contain a single, circular strand of DNA. A. DNA and Chromosomes. 2. Eukaryotes have 1000 times more DNA and it is more complicated. A. DNA and Chromosomes. 3. DNA Length
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A. DNA and Chromosomes • 1. Prokaryotes have no nucleus; contain a single, circular strand of DNA.
A. DNA and Chromosomes • 2. Eukaryotes have 1000 times more DNA and it is more complicated.
A. DNA and Chromosomes • 3. DNA Length • E.Coli Bacteria (large intestine) 4,639,221 Nitrogen Bases!! (1.6mm long)
A. DNA and Chromosomes • 4. Chromosome Structure • a. Nucleus of a human cell contains 1 meter of DNA! • b. Human DNA binds with protein called histones to form chromatin.
B. DNA Replication • 1. Replication is a copying process used by DNA to duplicate (copy) itself. • 2. During DNA replication, the DNA molecule separates.
B. DNA Replication • 3. Next, 2 new strands are made following the base pairing rules (A-T, C-G).
B. DNA Replication • 4. Each original strand of the double helix serves as a template for the 2 new strands (Semi-Conservative).
B. DNA Replication • 5. Many enzymes carry out replication (EX: Helicase unzips DNA) but the main enzyme is DNA Polymerase: • Joins nucleotides to make a DNA molecule • Proofreads DNA to correct mistakes animation