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Chronic Lung Disease Interventions

Chronic Lung Disease Interventions. N. Singhal University of Calgary November 2006. Outline. Process Interventions proposed Infection – K. Aziz CLD – N. Singhal Interventions implemented Infection – K. Aziz CLD – N. Singhal Future directions – K. Aziz. Review Process . Cochrane reviews

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Chronic Lung Disease Interventions

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  1. Chronic Lung DiseaseInterventions N. SinghalUniversity of CalgaryNovember 2006

  2. Outline • Process • Interventions proposed • Infection – K. Aziz • CLD – N. Singhal • Interventions implemented • Infection – K. Aziz • CLD – N. Singhal • Future directions – K. Aziz

  3. Review Process • Cochrane reviews • Systematic reviews • Informal reviews

  4. CLD Group Interventions • Process • Experts selected topics • Training provided for literature review • Each centre given ONE topic to review

  5. Review Process • Cochrane reviews • Systematic reviews • Informal reviews

  6. Process cont’d • Meeting of all centre/experts to discuss areas for improvement • Generated list of interventions

  7. Interventions Proposed • Antenatal • Treat urea plasma with erythromycin • Antenatal steroids

  8. Interventions Proposed • Resuscitation • Early within one hour prophylactic surfactant <28 weeks or <1250 g. • Diminish hand ventilation • Decrease 100% oxygen exposure

  9. Interventions Proposed • CPAP • Early CPAP for babies in supplemental oxygen • Long term CPAP

  10. Interventions Proposed • Ventilation • Early use of HFV

  11. Interventions Proposed • Normocarbia • Avoid hypocarbia • PaC02 40-55 mm of Hg

  12. Interventions Proposed • Saturation targets • Saturation targets • > 88 to < 94 ? 93

  13. Interventions Proposed • Nutrition/Fluids • Calories • Decrease fluid use • High dose Vitamin A

  14. Interventions Proposed • Environment • Pain • Massage • Noise • NIDCAP

  15. CLD Interventions Implemented • Antenatal: -Antibiotics -Expectant arrangement of PROM -Antenatal steroids

  16. CLD Interventions Implemented • Resuscitation • Surfactant within 30 minutes • Avoid hand ventilation • Ventilation delivery room • Only Laerdel bags with PEEP • Blended gases

  17. CLD Interventions Implemented • Ventilation • Early HVF – not done • Assist control and volume guarantee • Not done specifically

  18. CLD Interventions Implemented • Normocarbia • PaC02 – 45-55 mm of Hg

  19. CLD Interventions Implemented • Saturation targets • Sat alarm limits 85-95% • Goal 88-92% • Physician orders oxygen as drug

  20. CLD Interventions Implemented • Nutrition/Fluids • ↓ TFI < 32 weeks first few days • TPN within 24 hours • TPN within 4 hours

  21. CLD Interventions Implemented • Environment • Renovations to unit • ↓ sound levels

  22. CLD Interventions Implemented • Others: • Comment card for parents • Avoid re-intubation with CPAP • Perinatal referral policies

  23. > 27 weeks and < 34 weeks Extubate to CPAP if FiO2 <.4 (no time frame) Intubate, BLES Intubate, BLES transfer to NICU (*may be given in NICU after transfer) Extubate to CPAP if FiO2 <.4 at 2 to 4 hours of age and if clinically stable Stabilize then transfer to NICU Early CPAP – EPIC PDSA Cycle # 4 Respiratory Distress? (based on clinical judgment) Yes No Develops respiratory distress? No Routine management*** Yes Routine management*** Routine management*** If > 27 weeks, had HMD and on supplemental FiO2 in first 24 hours of life should be on CPAP *** wean from CPAP as per clinical indications

  24. Thank you

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