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Renal Adverse Effects of Drugs in Type 2 Diabetes and Cardiopathies

Heart failure (HF) can lead to a decline in renal function and adverse renal outcomes. This study explores the association between HF and increased risk of chronic kidney disease (CKD) and mortality. It also investigates the rapid decline in estimated glomerular filtration rate (eGFR) in HF patients.

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Renal Adverse Effects of Drugs in Type 2 Diabetes and Cardiopathies

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  1. Efectos adversos renales de los fármacos utilizados en pacientes con diabetes mellitus tipo 2 y cardiopatías Jose Ignacio Cornago Servicio de Nefrología. Hospital de Galdákano, Bilbao.

  2. Heart failure increases the risk of renal function decline and of adverse renal outcomesc HF is associated with significantly higher risk of incident CKD† and incident CKD or mortality HF is associated with a more rapid decline in eGFR* *Rapid rate of eGFR decline was defined as slopes steeper than -5 mL/min/1.73 m2/yr †Incident CKD was defined as two eGFR values of <60 mL/min/1.73 m2 occurring ≥3 months apart and a decrease from baseline eGFR of at least 25%. CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HF, heart failure. George LK, et al. Circ Heart Fail. 2017;10:e003825.

  3. PronosticImportanceofEarlyWorsening Renal Function after initiationofAngiotensin-ConvertinEnzimeInhibitorTherapy in PatientswithCardiacDysfunction

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