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Planning a family

Training. Planning a family. fertilo forte Denk 03.2015. Content. f ertilo forte Denk Product Information Key Selling Points Target Group Posology & Administration Ingredients Good to Know Sperm Quality Disorder Clinical Trials Good to Know Planning a Family Together

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Planning a family

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  1. Training Planning a family fertilo forte Denk 03.2015

  2. Content fertilo forte Denk Product Information Key Selling Points Target Group Posology & Administration Ingredients GoodtoKnow Sperm Quality Disorder Clinical Trials GoodtoKnow Planning a Family Together Additional Information About Male Infertility Other Denk Nutrition Products Train the Brain – Quiz References

  3. 1. fertilo forte Denk

  4. 2. Key SellingPoints • Very good compliance - only 1 stick per day • Easy consumption without water • 1 stick a day covers the recommended daily requirement of • micronutrients for normal spermatogenesis • Daily supplementation of fertiloforte improves male fertility1,2

  5. 3. Target Group • provides all important micronutrients • for men planning a family

  6. 4. Posology & Administration • INTAKE • The recommended intake is 1 stick per day taken after a meal • Easy consumption without water • INTAKE PERIOD • Minimum intake period is 3 months in order to optimize every step • of the spermatogenesis step. Recommendations It takes several months for a sperm cell to fully develop

  7. 5. Ingredients 1 Stick per day to increase male fertility and reproduction **No recommendation available

  8. 5. Ingredients SELENIUM contributes to normal spermatogenesis and to protection from oxidative stress ZINC contributes to normal fertility and reproduction and increases the testosterone level which is essential for sperm cell maturation FOLATE has a positive effect on sperm quality - especially sperm count and density1 VITAMIN E can improve the motility of sperms2 and contributes to the protection of cells from oxidative stress L- ARGININE AND L-CARNITINE can improve sperm cell motility3 COENZYM Q10 has antioxidant properties SELENIUM ZINC FOLATE VITAMIN E L-ARGININE L-CARNITINE CoenzymQ 10

  9. Train theBrain Explain the administration and posology of fertilo forte! One stick per day – easy consumption without water (ideally 3 months before planning a pregnancy)

  10. 6. Good to Know • Inadequate sperm production is not the fate of a minority • 6 % of all men have an unfulfilled desire for children even after one year of unprotected sex • Diagnosis: SPERMIOGRAM Test (normal sperm quality) World Health Organization reference values for human Semen characteristics, Cooper et al., Human Reproduction Update, Vol 16, No 3, 231-245, 2010

  11. 6. Good to Know • QUICK FACTS ABOUT (IN)FERTILITY • Sperm quality disorders have nothing to do with impotence • -> a man with an ejaculation is not always fertile • In approximately 40 percent of infertile couples, the male • partner is either the sole cause or a contributing cause of • infertility.1 • Seek expert opinion: Sperm quality test at a urologist – the • sooner ejaculate information acquired the sooner steps • can be taken to successfully conceive a child. Unmanly? Not at all! [1] American Society for Reproductive Medicine, http://www.asrm.org/detail.aspx?id=2322

  12. Train theBrain List the ingredients of fertilo forte! • Folate • Zinc • Coenzyme Q10 • Vitamine E • L-Arginine • L-Carnitine • Selenium

  13. 7. Sperm Quality Disorder Causes of sperm quality disorder: • Lifestyle • Stress, unhealthy eating habits • Smoking, use of alcohol or drugs • Medical • Congenital diseases • Hormone disorders • Variocele* • Infections (Chlamydia, gonorrhea, mumps) • Certain medications (Chemotherpy, anabolic steroid use) Age & Weight http://www.mayoclinic.org/diseases-conditions/male-infertility/basics/causes/con-20033113

  14. 8. Clinical Trials • L-Carnitine • Double-blind study: 60 men with normal sperm function were given either carnitine or placebo for 6 months. • Result: significant improvement of sperm function in the treated group compared to the placebo group Recommendations • Zinc plus Folate • 26-week, double-blind, 108 fertile men and 103 healthy men in placebo-controlled trial comparing the effect of zinc, folate, and zinc plus folate against placebo • Result: The combination of Zinc plus Folate significantly improved the sperm count and percentage of healthy sperms (no effect alone) • Antioxidants (Vitamin E, C) • Double-blind, placebo-controlled study, 110 men with subnormal sperm activity • Results: Daily treatment with IU of Vit E resulted in improved sperm activity and • increased rate of pregnancy in their partners Male infertility, Proposted treatments for male infertility, EBSCO CAM Review Board, 2011

  15. 9. GoodtoKnow Additional advice for turning lazy sperms into fit ones* • You are what you eat: Healthy balanced diet • Go nuts: Eat Walnuts and Vitamin C-rich fruits • Be physically active • Relax and avoid stress • Less smoking and drinking alcohol • Let loose: Avoid tight underpants

  16. 10. Planning a FamilyTogether FOR FATHERS -TO-BE may change your (family) life FOR MOTHERS -TO-BE

  17. 11. Additional Information About Male Infertility & Fertilo Forte WhatIsMale Infertility WhatIs A SpermCell? Male Infertility

  18. a) WhatIs Male Infertility? “Infertilityistheinabilityof a sexuallyactive, non-contraceptingcoupletoachievespontaneouspregnancy in oneyear.“ (WHO, 1995) • Possiblereasonsfor a reduction in male infertility: • Spermproductionproblems • Chromosomalorgeneticcauses • Undescendedtestes • Infections • Heat • Medicinesandchemicals • Malnutrition • Blockageofspermtransport • Infections • Prostaterelatedproblems • Spermantibodies • E.g. vasectomy • Sexual problems (erectionandejaculationproblems) • Hormonal problems • Congenital lack of LH/FSH • Anabolicsteroidabuse LH = luteinizinghormone, FSH = folliclestimulatinghormone

  19. b) WhatIs A SpermCell? Didyouknow, that…? Zincandfolicacidare essential forhealthycellreplication The developmentof a maturespermcellfromthestem stell stagetakesabout70 days The average man will produce525 billionspermcellsoverhislifetime Productionofspermcells (= spermatogenesis)

  20. c) Male Infertility • Itisimportanttodistinguishbetween • → quiteoften, all threepathologiesoccur at the same time, i.e. asoligo-astheno-teratozoospermia Teratozoo-spermia (< 4% normal forms) Oligozoospermia (< 15 millionspermatozoa/ml) Asthenozoo-spermia (< 40% motilespermatozoa)

  21. 12. Other Denk Nutrition Products Well tolerated iron supplement Fast supply of magnesium to muscles, heart and nerves For iron deficiency in pregnancy & Breast-feeding Reduces cramps during pregnancy Reduction of tiredness & fatigue

  22. 13. Train the Brain – Quiz! Explain the administration and posology of fertilo forte! What is the target group of fertilo forte? List the ingredients of fertilo forte! What are the causes of sperm quality disorders?

  23. 13. Train the Brain – Quiz! 1. One stick per day – easy consumption without water (ideally 3 months before planning a pregnancy) 2. Men planning a family 3. Folate, Zinc, Coenzyme Q10, Vitamine E, L-Arginine, L-Carnitine, Selenium 4. Bad nutrition habits, stress, old age and weight, medical causes (e.g. infections, hormonal disorders), alcohol consumption, prostate related problems, hormonal problems and smoking

  24. 14. References • http://www.beliefnet.com/healthandhealing/getcontent.aspx?cid=157009, Oldereid et al., Lifestyles of men in barren couples and their relationships to sperm quality, Eur J ObstetGynecolReprodBiol, 1992 Jan 9;43(1):51-7. http://www.who.int/reproductivehealth/topics/infertility/definitions/en/ • A. Jungwirth, Guidelines forthe Investigation and Treatment of Male Infertility, 2012 • http://www.joanmoloneynutrition.ie/2012/02/15/men%E2%80%99s-health-%E2%80%93-improving-sperm-production-with-foods/ • Wallock et al., Low seminal plasma folate concentrations are assocaited with low sperm density and count in male smokers and nonsmokers, Fertil. Steril 2001, 75 (2), 252-9 • Suleiman et al., Lipid peroxidation and human sperm motility: protective role of vitamin E., J Anrol 1996; 17: 530-7 • Walnuts improve Semen Quality in Men Consuming a Western-style Diet: Randomized Control Dietary Intervention Trial, Robbins et al., Biology of Reproduction, 2012

  25. Join Denk Pharma! Our contributions to keeping you* healthy: • affordable pharmaceuticals for your therapy • German high premium quality for tablets, sachets, • packaging, studies, consultation, availability, support, etc… • raise awareness by conducting Check Up Days (blood glucose, • blood pressure, cholesterol and triglyceride) • constantly enhancing the product portfolio *patients, doctors, pharmacists, sales reps

  26. HEALTHCARE MADE IN GERMANY since 1948

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