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Nicotine. Adam Hoza Alexandra Rychová. What is nicotine?. pyridin-N-metylpyrrolidin liquid alkaloid included in tobacco is bound to acid apple or lemonish and his quantity in plant notching as far as 8% is washable and dozen
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Nicotine Adam Hoza Alexandra Rychová
What is nicotine? • pyridin-N-metylpyrrolidin • liquid alkaloid included in tobacco • is bound to acid apple or lemonish and his quantity in plant notching as far as 8% • is washable and dozen • fresh is odourless, otherwise dirtily smells and tastespungently
Effects of nicotine on man • has ability to liberate dopamin thereby evoke pleasant feelings • helps smokers to refresh memory namely thanks to activation of acetylcholine steps • releases epinephrine from suprarenal gland • works vegetative nerve knot, NS plate, CNS (at overdosing shake) • turns sensation taste foods and sensation enjoyment from foods
Why is nicotine so dangerous? • mitotic poisoning of organoleptic nucleus of a cell (fatal dose is 50mg) • at high taxs: overall attenuation of CNS> apneusis > death • manifestations of poisoning: nauzea, vomit, diarrhoea, salivation, cold sweat, fuzziness
How does nicotine get to human body? • row plants include nicotine, they come largely from America • mostly nicotine is included in tobacco (0.6-8%) • to the bodies it gets by smoking, snuff or chewing leafs • nicotinic receptors respond very fast • Incidence on body is up to several minutes, however way nicotine goes from lungs to the brain nicotine mere 7,5 seconds
Something about the story of tobacco • During Antiquity and Middle Ages Europe didn‘t know about tobacco • First tobacco was taken to Europe by Kolumbus in the year 1492 • Seeds of tobacco got here some about 20 years later • Biggest worth has Frenchman Jean Nicotothat who took it to French court in 1560, namely in develoment of practice of snuffing powder
Diseases incurred by smoking • Cardio-vascular disorder (25%) • Tuberculous disorder (30%) • Chronic pulmonary disorder(75%) červeně je zobrazena celková úmrtnost v ČR, zeleně choroby související s kouřením; oboje vztaženo na 100.000 obyvatel