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Explore the fundamentals of organic chemistry focusing on ethers, their preparation, testing for peroxides, Grignard reagent, and cleavage methods. Learn about symmetrical and unsymmetrical ethers, epoxides, and reactions with nucleophiles in cyclic ethers.
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Organic chemistry for medicine and biology students Chem 2311 Chapter 8 Ethers By Prof. Dr. Adel M. Awadallah Islamic University of Gaza
Preparation of Ethers • Symmetrical ethers (from alcohols) B) Unsymmetrical ethers (Williamson’s Synthesis)
Cleavage of Ethers Ethers are cleaved by strong acids such as HI
Epoxides (Oxiranes) Cyclic ethers with a three-membered rings
Reactions of Epoxides When attacked by nucleophiles, epoxides undergo acid catalized ring opening.